Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 9/20 | 0.70 |
| ▸ | THRB | P10828 | 9/20 | 0.70 |
| ▸ | RARB | P10826 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | RARA | P10276 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | MTOR | P42345 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.61 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962497 | 1.00 | THRA (0.70) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL28455281 | 1.00 | THRA (0.70) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL12457863 | 1.00 | THRA (0.70) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL28733046 | 1.00 | THRA (0.70) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL965453 | 1.00 | THRA (0.70) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL8383207 | 1.00 | THRA (0.70) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL499485 | 1.00 | THRA (0.70) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9997622 | 1.00 | THRA (0.70) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL965858 | 1.00 | THRA (0.70) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL1133493 | 1.00 | THRA (0.70) | THRATHRBRARBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076314-A1 | Bisphenol compound and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2009-03-19 | — | — | US | claimed |
| US-20070073090-A1 | Bisphenol compound and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2007-03-29 | — | — | US | claimed |
| US-20090076314-A1 | Bisphenol compound and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2009-03-19 | — | — | US | disclosed |
| US-20090076314-A1 | Bisphenol compound and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2009-03-19 | — | — | US | disclosed |
| US-7446234-B2 | Bisphenol compound and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-11-04 | — | — | US | disclosed |
| US-7446234-B2 | Bisphenol compound and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-11-04 | — | — | US | disclosed |
| US-20070073090-A1 | Bisphenol compound and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2007-03-29 | — | — | US | disclosed |
| US-20070073090-A1 | Bisphenol compound and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076314-A1 | Bisphenol compound and process for preparation thereof | DOT1L, ACSL3, ASH1L | THRA 2823/4885THRB 2455/4885RARB 2321/4885 |
| US-20070073090-A1 | Bisphenol compound and process for preparation thereof | DOT1L, ACSL3, ASH1L | THRA 2823/4885THRB 2455/4885RARB 2321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.