SCHEMBL499485

SCHEMBL499485

CCCCCCCc1ccc(C(C)=O)cc1

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRA P10827 9/20 0.70
THRB P10828 9/20 0.70
RARB P10826 5/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
ALDH1A1 P00352 1/20 0.67
RARA P10276 1/20 0.67
MAPT P10636 1/20 0.67
MTOR P42345 1/20 0.67
HSD17B10 Q99714 1/20 0.62
PLA2G1B P04054 3/20 0.61
ATG4B Q9Y4P1 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL962497 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL28455281 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL12457863 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL28733046 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL965453 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL8383207 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL9997622 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL4185050 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL965858 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A
SCHEMBL1133493 1.00 THRA (0.70) THRATHRBRARBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117778073-A High-efficiency polymerization inhibitor for sulfur-free odorizing agent 辽宁厚安科技有限公司 2024-03-29 CN claimed
WO-2023217050-A1 POLYMER AND PREPARATION METHOD THEREFOR, AND ANION-EXCHANGE MEMBRANE 嘉庚创新实验室 2023-11-16 WO claimed
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2026-03-05 US disclosed
EP-3954745-B1 REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) 2026-01-07 EP disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
US-12421411-B2 Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument KABUSHIKI KAISHA PILOT CORPORATION (JP) 2025-09-23 US disclosed
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
US-12123107-B2 Reversibly thermochromic composite fiber KABUSHIKI KAISHA PILOT CORPORATION (JP) 2024-10-22 US disclosed
US-12011943-B2 Image forming apparatus TOSHIBA TEC KABUSHIKI KAISHA (JP) 2024-06-18 US disclosed
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-117778073-A High-efficiency polymerization inhibitor for sulfur-free odorizing agent 辽宁厚安科技有限公司 2024-03-29 CN disclosed
US-5558699-A COLOR IS RETAINED AFTER HEATING OR COOLING IS WITHDRAWN, REACTION MEDIUM IS ALKYL OR ALKYLARYL KETONE THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
EP-0339252-B1 2,5-disubstituted pyrazine derivatives, pyrimidine derivatives, and liquid crystal containing the same DAINIPPON INK & CHEMICALS (JP) 1996-06-12 EP disclosed
EP-0665119-A1 Thermochromic colour-memory composition THE PILOT INK CO., LTD. (JP) 1995-08-02 EP disclosed
EP-0306195-B1 Optically active-2,5-diphenylpyridines CHISSO CORP (JP) 1994-03-16 EP disclosed
US-5128472-A Electrooptical display materials, ferroelectric display DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-07-07 US disclosed
US-5047171-A Liquid Crystals CHISSO CORPORATION (JP) 1991-09-10 US disclosed
US-4997942-A 2,4-disubstituted pyrazine derivatives, pyrimidine derivatives, and liquid crystal containing the same DAINIPPON INK AND CHEMICAL, INC. (JP) 1991-03-05 US disclosed
EP-0339252-A2 2,5-disubstituted pyrazine derivatives, pyrimidine derivatives, and liquid crystal containing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-11-02 EP disclosed
EP-0306195-A2 Optically active-2,5-diphenylpyridines Chisso Corporation (JP) 1989-03-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT TYR, SCO2, HBB THRA 2057/4885THRB 542/4885RARB 334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.