Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13875613 | 0.88 | MAPT (0.38) | NR1H3NR1H2MAPTLMNAHTT | |
| SCHEMBL1766724 | 0.85 | MAPT (0.43) | NR1H3NR1H2MAPTLMNAHTT | |
| SCHEMBL1766807 | 0.85 | NR1H3 (0.43) | NR1H3NR1H2MAPTLMNAHTT | |
| SCHEMBL4184912 | 0.83 | KCNK3 (0.48) | MAPTLMNAMEN1KMT2AHPGD | |
| SCHEMBL4183073 | 0.83 | NR1H3 (0.40) | NR1H3NR1H2MAPTLMNAHTT | |
| SCHEMBL4185515 | 0.81 | NR1H3 (0.39) | NR1H3NR1H2MAPTLMNAHTT | |
| SCHEMBL1766921 | 0.81 | MAPT (0.41) | NR1H3NR1H2MAPTLMNAHTT | |
| SCHEMBL4188926 | 0.81 | UGCG (0.42) | NR1H3NR1H2MAPTLMNAHTT | |
| SCHEMBL20846720 | 0.80 | SIRT2 (0.38) | NR1H3NR1H2MAPTLMNAHTT | |
| SCHEMBL1766411 | 0.80 | NR1H3 (0.46) | NR1H3NR1H2MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099204-A1 | Amide derivative, insecticide containing the same and method for application thereof as insecticide | MITSUI CHEMICALS, INC. (JP) | 2009-04-16 | — | — | US | disclosed |
| EP-1916236-A1 | AMIDE DERIVATIVE, PESTICIDE CONTAINING SUCH COMPOUND AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099204-A1 | Amide derivative, insecticide containing the same and method for application thereof as insecticide | CYP2E1, GSTA1, CYP2S1 | NR1H3 362/4885NR1H2 384/4885MAPT 4640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.