Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9921691 | 0.85 | ATM (0.76) | ALDH1A1LMNAATMSMN1; SMN2HPGD | |
| SCHEMBL403057 | 0.81 | ATM (0.74) | ALDH1A1LMNAATMSMN1; SMN2HPGD | |
| SCHEMBL3216808 | 0.81 | ATM (0.74) | ALDH1A1LMNAATMSMN1; SMN2HPGD | |
| SCHEMBL6555426 | 0.81 | ALDH1A1 (0.80) | ALDH1A1LMNAMAPTATMSMN1; SMN2 | |
| SCHEMBL13025526 | 0.81 | ATM (0.74) | ALDH1A1LMNAATMSMN1; SMN2HPGD | |
| SCHEMBL10122851 | 0.81 | LMNA (1.00) | ALDH1A1LMNAMAPTATMSMN1; SMN2 | |
| SCHEMBL21671899 | 0.81 | ATM (0.68) | ALDH1A1LMNAMAPTATMSMN1; SMN2 | |
| SCHEMBL22793773 | 0.81 | ATM (0.68) | ALDH1A1LMNAATMSMN1; SMN2HPGD | |
| SCHEMBL22793764 | 0.81 | ATM (0.68) | ALDH1A1LMNAATMSMN1; SMN2HPGD | |
| SCHEMBL8338968 | 0.80 | HRH3 (0.73) | ALDH1A1LMNAMAPTATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | BIOTIE THERAPIES CORP. (FI) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023735-A1 | Sulphonamide Derivatives | HCAR1, ADGRE5, ALK | ALDH1A1 872/4885LMNA 1673/4885MAPT 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.