Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL11318959 | 0.95 | ESR1 (0.41) | ALDH1A1ESR1CYP2D6CYP3A4SLC6A2 | |
| Diethylamine SCHEMBL6512053 | 0.89 | ACP3 (0.42) | ESR1CYP2D6CYP3A4SLC6A2SLC6A4 | |
| Diethylamine SCHEMBL8165175 | 0.89 | ACP3 (0.42) | ESR1CYP2D6CYP3A4SLC6A2SLC6A4 | |
| Diethylamine SCHEMBL4185484 | 0.86 | ACP3 (0.42) | ESR1CYP2D6CYP3A4SLC6A2SLC6A4 | |
| Diethylamine SCHEMBL6365629 | 0.85 | ESR1 (0.45) | ALDH1A1ESR1CYP2D6CYP3A4SLC6A2 | |
| Diethylamine SCHEMBL10775399 | 0.84 | ALDH1A1 (0.43) | ALDH1A1ESR1CNR2ACP3OPRM1 | |
| Diethylamine SCHEMBL237985 | 0.83 | ESR1 (0.43) | ALDH1A1ESR1CYP2D6CYP3A4SLC6A2 | |
| Diethylamine SCHEMBL10780343 | 0.82 | ESR1 (0.42) | ALDH1A1ESR1CYP2D6CYP3A4SLC6A2 | |
| Diethylamine SCHEMBL10778585 | 0.78 | HTT (0.41) | ALDH1A1ESR1SLC6A4KCNH2LMNA | |
| Diethylamine SCHEMBL6271332 | 0.77 | ESR1 (0.45) | ALDH1A1ESR1CYP2D6CYP3A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119755-B1 | SENSITIZED PHOTOCONDUCTIVE COMPOSITIONS AND ELEMENTS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-12-02 | — | — | EP | claimed |
| EP-0119755-A2 | Sensitized photoconductive compositions and elements | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-09-26 | — | — | EP | claimed |
| US-4468444-A | Pyrylium-sensitized leuco base photoconductive compositions and elements containing naphthalene bis-dicarboximide compounds | EASTMAN KODAK COMPANY (US) | 1984-08-28 | — | — | US | claimed |
| US-4442193-A | SENSITIZED TO RADIATION BELOW 400 NANOMETERS | EASTMAN KODAK COMPANY (US) | 1984-04-10 | — | — | US | claimed |
| EP-0011980-B1 | PHOTOCONDUCTIVE LAYERS CONTAINING A MIXTURE OF AT LEAST TWO DIFFERENT ORGANIC PHOTOCONDUCTORS AND ELECTROPHOTOGRAPHIC ELEMENTS COMPRISING SAID LAYERS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-03-28 | — | — | EP | claimed |
| EP-0011980-A1 | Photoconductive layers containing a mixture of at least two different organic photoconductors and electrophotographic elements comprising said layers | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1980-06-11 | — | — | EP | claimed |
| US-20220112996-A1 | JEWELRY AND GEM STONE LIGHTING SYSTEMS AND APPARATUSES AND METHOD MAKING AND USING SAME | ASHLEY PAUL (US) | 2022-04-14 | — | — | US | disclosed |
| US-11018303-B2 | Charge-transporting varnish | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2021-05-25 | — | — | US | disclosed |
| EP-3053910-B1 | ANILINE DERIVATIVES AND USES THEREOF | NISSAN CHEMICAL CORP (JP) | 2021-04-28 | — | — | EP | disclosed |
| EP-3109914-B1 | CHARGE-TRANSPORTING VARNISH | NISSAN CHEMICAL CORP (JP) | 2021-04-28 | — | — | EP | disclosed |
| US-20210078934-A1 | CHARGE-TRANSPORTING VARNISH | NISSAN CHEMICAL CORPORATION (JP) | 2021-03-18 | — | — | US | disclosed |
| US-20210061825-A1 | ANILINE DERIVATIVE AND USE THEREOF | NISSAN CHEMICAL CORPORATION (JP) | 2021-03-04 | — | — | US | disclosed |
| EP-3766887-A1 | ANILINE DERIVATIVE AND USE THEREOF | Nissan Chemical Corporation (JP) | 2021-01-20 | — | — | EP | disclosed |
| US-4686163-A | Electrophotographic color imaging method | EASTMAN KODAK COMPANY (US) | 1987-08-11 | — | — | US | disclosed |
| US-4600669-A | Electrophotographic color proofing element and method for using the same | EASTMAN KODAK COMPANY (US) | 1986-07-15 | — | — | US | disclosed |
| EP-0186172-A1 | Electrophotographic color proofing method | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-07-02 | — | — | EP | disclosed |
| EP-0119755-A2 | Sensitized photoconductive compositions and elements | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4468444-A | Pyrylium-sensitized leuco base photoconductive compositions and elements containing naphthalene bis-dicarboximide compounds | EASTMAN KODAK COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| US-4442193-A | SENSITIZED TO RADIATION BELOW 400 NANOMETERS | EASTMAN KODAK COMPANY (US) | 1984-04-10 | — | — | US | disclosed |
| EP-0011980-B1 | PHOTOCONDUCTIVE LAYERS CONTAINING A MIXTURE OF AT LEAST TWO DIFFERENT ORGANIC PHOTOCONDUCTORS AND ELECTROPHOTOGRAPHIC ELEMENTS COMPRISING SAID LAYERS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061825-A1 | ANILINE DERIVATIVE AND USE THEREOF | NAT1, DRD3, AR | ALDH1A1 349/4885ESR1 898/4885CNR1 216/4885 |
| US-20210078934-A1 | CHARGE-TRANSPORTING VARNISH | SLC43A1, SLC7A5, SLC38A7 | ALDH1A1 967/4885ESR1 1912/4885CNR1 2090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.