Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4179389 | 0.81 | HSD11B1 (0.39) | HSD11B1ALDH1A1LMNAMAPTGFER | |
| SCHEMBL4179397 | 0.81 | HSD11B1 (0.39) | HSD11B1ALDH1A1LMNAMAPTGFER | |
| SCHEMBL4179392 | 0.81 | HSD11B1 (0.39) | HSD11B1ALDH1A1LMNAMAPTGFER | |
| SCHEMBL4185422 | 0.80 | HSD11B1 (0.38) | HSD11B1ALDH1A1LMNAMAPTGFER | |
| SCHEMBL4184940 | 0.80 | NPSR1 (0.39) | HSD11B1ALDH1A1LMNAMAPTGFER | |
| SCHEMBL4181612 | 0.79 | HSD11B1 (0.36) | HSD11B1ALDH1A1LMNAMAPTGFER | |
| SCHEMBL5963959 | 0.79 | HSD11B1 (0.39) | HSD11B1ALDH1A1LMNAMAPTGFER | |
| SCHEMBL4175723 | 0.78 | NPBWR1 (0.37) | HSD11B1ALDH1A1LMNAMAPTGFER | |
| SCHEMBL4175719 | 0.78 | NPBWR1 (0.37) | HSD11B1ALDH1A1LMNAMAPTGFER | |
| SCHEMBL5964510 | 0.77 | MMP1 (0.39) | ALDH1A1CCR1CCR2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186868-A1 | Taxane Compound Having Azetidine Ring Structure | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-07-23 | — | — | US | disclosed |
| US-20090186868-A1 | Taxane Compound Having Azetidine Ring Structure | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-1942109-A1 | TAXANE COMPOUND WITH AZETIDINE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186868-A1 | Taxane Compound Having Azetidine Ring Structure | ABCC1, AZI2, TPD52L2 | HSD11B1 1690/4885ALDH1A1 664/4885LMNA 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.