Methacrylic Acid

Methacrylic Acid

SCHEMBL418671

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.OCC(O)C(CO)CO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.39
PDE4A P27815 1/20 0.37
LMNA P02545 3/20 0.34
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
OR51E2 Q9H255 1/20 0.33
TET2 Q6N021 4/20 0.32
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL6858413 0.90 LMNA (0.47) TGFBR1PDE4ALMNAUSP2SLCO1B1
E968 SCHEMBL4778196 0.88 TGFBR1 (0.43) TGFBR1PDE4ALMNAUSP2SLCO1B1
E968 SCHEMBL960729 0.88 TGFBR1 (0.43) TGFBR1PDE4ALMNAUSP2SLCO1B1
E968 SCHEMBL27092634 0.88 TGFBR1 (0.43) TGFBR1PDE4ALMNAUSP2SLCO1B1
E968 SCHEMBL9847628 0.88 TGFBR1 (0.43) TGFBR1PDE4ALMNAUSP2SLCO1B1
E968 SCHEMBL2152820 0.88 TGFBR1 (0.43) TGFBR1PDE4ALMNAUSP2SLCO1B1
E968 SCHEMBL7107678 0.88 TGFBR1 (0.43) TGFBR1PDE4ALMNAUSP2SLCO1B1
E968 SCHEMBL3651326 0.88 TGFBR1 (0.43) TGFBR1PDE4ALMNAUSP2SLCO1B1
E968 SCHEMBL6433622 0.88 TGFBR1 (0.43) TGFBR1PDE4ALMNAUSP2SLCO1B1
E968 SCHEMBL18784099 0.88 TGFBR1 (0.43) TGFBR1PDE4ALMNAUSP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2399953-B1 POLYCHLOROPRENE ELASTOMER COMPOSITION, PROCESS FOR PRODUCING SAME, AND VULCANIZATE AND MOLDED OBJECT DENKA COMPANY LTD (JP) 2017-03-15 EP disclosed
US-20120022196-A1 POLYCHLOROPRENE ELASTOMER COMPOSITION, AND PRODUCTION METHOD- AND THE VULCANIZATE AND MOLDED ARTICLES THEREOF DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2012-01-26 US disclosed
EP-2399953-A1 POLYCHLOROPRENE ELASTOMER COMPOSITION, PROCESS FOR PRODUCING SAME, AND VULCANIZATE AND MOLDED OBJECT Denki Kagaku Kogyo Kabushiki Kaisha (JP) 2011-12-28 EP disclosed