SCHEMBL4187650

SCHEMBL4187650

CCCCCC[C@@H](O)C/C=C\CCCCCCCC(=O)O[C@H]1[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.47
FFAR4 Q5NUL3 1/20 0.47
TLR4 O00206 5/20 0.47
CETP P11597 1/20 0.45
SELP P16109 1/20 0.45
FAAH O00519 1/20 0.44
APP P05067 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4187653 0.95 FFAR1 (0.47) FFAR1FFAR4TLR4CETPSELP
SCHEMBL2959757 0.91 TLR4 (0.54) TLR4CETPSELP
SCHEMBL7532141 0.88 TLR4 (0.56) TLR4CETPSELP
SCHEMBL2959758 0.85 TLR4 (0.54) TLR4CETPSELP
SCHEMBL3388845 0.85 GJB2 (0.50) TLR4
SCHEMBL3393530 0.85 GJB2 (0.50) TLR4
SCHEMBL4185389 0.85 GJB2 (0.50) TLR4
SCHEMBL4199466 0.85 GJB2 (0.50) TLR4
SCHEMBL4181281 0.85 GJB2 (0.50) TLR4
SCHEMBL4185267 0.85 GJB2 (0.50) TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090098172-A1 SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME KAO CORPORATION (JP) 2009-04-16 US disclosed
US-20070292462-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant KAO CORPORATION (JP) 2007-12-20 US disclosed
US-20070160556-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant IKEMOTO TAKESHI 2007-07-12 US disclosed
US-6497898-B1 STABILITY, DRUG AND COSMETIC DELIVERY KANEBO LTD (JP) 2002-12-24 US disclosed
EP-0729781-B1 LIPOSOME COMPRISING A MEMBRANE WALL COMPOSED OF A TREHALOSE FATTY ACID ESTER KANEBO LTD (JP) 2002-08-07 EP disclosed
EP-0729781-A1 SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME Ikemoto, Takeshi (JP) 1996-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070292462-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant TREH, LIPA, CUTA FFAR1 40/4885FFAR4 74/4885TLR4 477/4885
US-20070160556-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant TREH, LIPA, CUTA FFAR1 40/4885FFAR4 74/4885TLR4 477/4885
US-20090098172-A1 SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME TREH, LIPA, SGMS1 FFAR1 59/4885FFAR4 118/4885TLR4 513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.