Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4193707 | 0.97 | SMN1; SMN2 (0.47) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL26137982 | 0.86 | DNM1 (0.40) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL26138010 | 0.86 | DNM1 (0.40) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL26138012 | 0.85 | BCHE (0.39) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL26138011 | 0.85 | DNM1 (0.39) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL6574042 | 0.79 | DNM1 (0.50) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL20520489 | 0.77 | TAAR1 (0.43) | MEN1KMT2ASMN1; SMN2HTTCYP3A4 | |
| Tetrabuthylammonium SCHEMBL5470043 | 0.77 | SLC22A1 (0.57) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL2059991 | 0.77 | MEN1 (0.71) | MEN1KMT2ATP53SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL5086997 | 0.77 | MEN1 (0.71) | MEN1KMT2ATP53SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312918-B1 | Oxygen detecting composition | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-02-18 | — | — | EP | disclosed |
| US-6703245-B2 | Oxygen detecting composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-03-09 | — | — | US | disclosed |
| EP-1312918-A2 | Oxygen detecting composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-20030082823-A1 | Oxygen detecting composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-05-01 | — | — | US | disclosed |