Fosfonet

Fosfonet

SCHEMBL418897

CCCC.O=C(O)CP(=O)(O)O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.78
LMNA P02545 1/20 0.78
HPGD P15428 1/20 0.78
TSHR P16473 1/20 0.78
BLM P54132 1/20 0.78
KMT2A Q03164 1/20 0.78
TDP1 Q9NUW8 1/20 0.78
FFAR3 O14843 2/20 0.41
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
FDPS P14324 2/20 0.40
ENO1 P06733 1/20 0.40
PGK1 P00558 1/20 0.39
PGK2 P07205 1/20 0.39
LPAR3 Q9UBY5 3/20 0.39
LPAR2 Q9HBW0 1/20 0.39
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fosfonet SCHEMBL25402251 0.89 MEN1 (0.78) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL9377672 0.89 MEN1 (0.61) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL15612 0.88
Fosfonet SCHEMBL347045 0.86 MEN1 (0.82) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL4607410 0.85 MEN1 (0.93) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL9162319 0.85
Fosfonet SCHEMBL2801407 0.85
Fosfonet SCHEMBL11026013 0.85
Fosfonet SCHEMBL15510455 0.85 MEN1 (0.93) MEN1LMNAHPGDTSHRBLM
Fosfonet SCHEMBL28151124 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023207268-A1 SYNTHESIS METHOD OF PLANT-DERIVED DEOXYCHOLIC ACID 上海科骊科生物技术有限公司 2023-11-02 WO claimed
CN-115536719-A Synthetic method of high-purity plant source 7-ketolithocholic acid 江苏佳尔科药业集团股份有限公司 2022-12-30 CN claimed
CN-113354954-B Cationic photocuring epoxy vegetable oil-based flame-retardant material and preparation method and application thereof 华南农业大学 2022-04-26 CN claimed
CN-113354954-A Cationic photocuring epoxy vegetable oil-based flame-retardant material and preparation method and application thereof 华南农业大学 2021-09-07 CN claimed
WO-2021109791-A1 METHOD FOR SYNTHESIZING URSODEOXYCHOLIC ACID USING BA AS RAW MATERIAL 江苏佳尔科药业集团股份有限公司 2021-06-10 WO claimed
CN-104529800-A Preparation method of trans-4-dimethylaminocrotonic acid and its salt CHONGQING WEIPENG PHARMACEUTICAL CO LTD 2015-04-22 CN claimed
CN-1867564-B Process for producing amino crotonyl compound BOEHRINGER INGELHEIM INT 2011-06-08 CN claimed
CN-1867564-A Process for producing amino crotonyl compound BOEHRINGER INGELHEIM INT (DE) 2006-11-22 CN claimed
JP-5331093-A None JP disclosed
US-12441759-B2 Method for synthesizing ursodeoxycholic acid using BA as raw material JIANGSU JIAERKE PHARMACEUTICALS GROUP CORP., LTD. (CN) 2025-10-14 US disclosed
US-12415789-B2 Macrocycles comprising a 4-amido-2,4-pentadienoate moiety for the treatment of hypoxic cancers AARHUS UNIVERSITET (DK) 2025-09-16 US disclosed
CN-120119112-A Method for recovering aluminum matrix from aluminum target containing indium-tin solder 新疆众和股份有限公司 2025-06-10 CN disclosed
US-12233081-B2 Hygromycin a compounds and methods of treating spirochete diseases NORTHEASTERN UNIVERSITY (US) 2025-02-25 US disclosed
CN-119340518-A Lithium secondary battery and assembly 大金工业株式会社 2025-01-21 CN disclosed
JP-H05331093-A INTERMEDIATE FOR 1,25-DIHYDROXYVITAMIN D3 TAISHO PHARMACEUT CO LTD 1993-12-14 JP disclosed
EP-0454494-A2 Calicheamicinone, derivatives and analogs thereof and methods of making the same YALE UNIVERSITY (US) 1991-10-30 EP disclosed
US-5059610-A QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-10-22 US disclosed
US-4920132-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed
EP-0330939-A2 Acrylic acid morpholides, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-09-06 EP disclosed
EP-0199618-A1 5-H-pyrido[3',4':4,5]pyrrolo[3,2-c]pyridones, process for their preparation and their use as intermediate synthesis compounds SANOFI (FR) 1986-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12233081-B2 Hygromycin a compounds and methods of treating spirochete diseases TREH, GBA1, HSP90AB1 MEN1 409/4885LMNA 604/4885HPGD 902/4885
US-12441759-B2 Method for synthesizing ursodeoxycholic acid using BA as raw material CYP7A1, DHCR7, CYP46A1 MEN1 3844/4885LMNA 2312/4885HPGD 347/4885
US-12415789-B2 Macrocycles comprising a 4-amido-2,4-pentadienoate moiety for the treatment of hypoxic cancers DLD, HIF1A, DPYD MEN1 3400/4885LMNA 4294/4885HPGD 124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.