Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2426899 | 0.92 | LMNA (0.37) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL4210408 | 0.87 | AKR1B1 (0.38) | LMNACES1CES2AKR1B1TDP1 | |
| SCHEMBL28660181 | 0.83 | AKR1B1 (0.50) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL3618428 | 0.78 | AKR1B1 (0.55) | PTGS1AKR1B1TDP1HPGD | |
| SCHEMBL13586796 | 0.76 | LMNA (0.56) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL7410335 | 0.75 | LMNA (0.72) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL11879591 | 0.73 | LMNA (0.75) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL28668160 | 0.73 | AKR1B1 (0.46) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL77563 | 0.73 | CES1 (0.70) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL5326692 | 0.73 | PKM (0.36) | LMNAGAAAKR1B1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476416-B1 | MULTIFUNCTIONAL MONOMERS AND THEIR USE IN MAKING CROSS-LINKED POLYMERS AND POROUS FILMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-12-30 | — | — | EP | disclosed |
| US-7635741-B2 | Curable polyacetylenes used as dielectrics in making microelectronics such as integrated circuits | DOW GLOBAL TECHNOLOGIES INC. | 2009-12-22 | — | — | US | disclosed |
| US-20070037894-A1 | Multifunctional menomers and polyarylene compsotions therefrom | HAHNFELD JERRY L | 2007-02-15 | — | — | US | disclosed |
| US-20070027280-A1 | Multifunctional substituted monomers and polyarylene compositions therefrom | HAHNFELD JERRY L | 2007-02-01 | — | — | US | disclosed |
| US-20040053033-A1 | Multifunctional monomers and their use in making cross-linked polymers and porous films | NIU Q JASON (US) | 2004-03-18 | — | — | US | disclosed |