SCHEMBL4189789

SCHEMBL4189789

CCCCCCC(O)CCCCCO[C@@H]1[C@@H](O)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O[C@H](CO)[C@H]1O

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GJB2 P29033 3/20 0.51
▸ LGALS8 O00214 3/20 0.49
▸ LGALS3 P17931 3/20 0.49
▸ LGALS4 P56470 3/20 0.49
▸ SELL P14151 2/20 0.48
▸ SELP P16109 2/20 0.48
▸ MAPK1 P28482 1/20 0.47
▸ TLR4 O00206 1/20 0.47
▸ CETP P11597 1/20 0.45
▸ GBA1 P04062 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7533799 0.92 GJB2 (0.57) GJB2LGALS8LGALS3LGALS4SELL
SCHEMBL27059132 0.86 MAPK1 (0.53) LGALS8LGALS3LGALS4SELLSELP
SCHEMBL27060552 0.86 MAPK1 (0.53) LGALS8LGALS3LGALS4SELLSELP
SCHEMBL29335761 0.86 MAPK1 (0.53) LGALS8LGALS3LGALS4SELLSELP
SCHEMBL29335235 0.86 MAPK1 (0.53) LGALS8LGALS3LGALS4SELLSELP
SCHEMBL13576466 0.83 CETP (0.53) LGALS8LGALS3LGALS4SELLSELP
SCHEMBL12507198 0.83 CETP (0.53) LGALS8LGALS3LGALS4SELLSELP
SCHEMBL21537087 0.83 CETP (0.53) LGALS8LGALS3LGALS4SELLSELP
SCHEMBL13356315 0.83 CETP (0.53) LGALS8LGALS3LGALS4SELLSELP
SCHEMBL18464541 0.83 CETP (0.53) LGALS8LGALS3LGALS4SELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090098172-A1 SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME KAO CORPORATION (JP) 2009-04-16 — — US disclosed
US-20070292462-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant KAO CORPORATION (JP) 2007-12-20 — — US disclosed
US-20070160556-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant IKEMOTO TAKESHI 2007-07-12 — — US disclosed
US-20040022819-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant KAO CORPORATION (JP) 2004-02-05 — — US disclosed
US-6497898-B1 STABILITY, DRUG AND COSMETIC DELIVERY KANEBO LTD (JP) 2002-12-24 — — US disclosed
EP-0729781-A1 SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME Ikemoto, Takeshi (JP) 1996-09-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070292462-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant TREH, LIPA, CUTA GJB2 4097/4885LGALS8 806/4885LGALS3 1210/4885
US-20040022819-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant TREH, LIPA, CUTA GJB2 4049/4885LGALS8 828/4885LGALS3 1182/4885
US-20070160556-A1 Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant TREH, LIPA, CUTA GJB2 4097/4885LGALS8 806/4885LGALS3 1210/4885
US-20090098172-A1 SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME TREH, LIPA, SGMS1 GJB2 4241/4885LGALS8 983/4885LGALS3 1166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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