SCHEMBL4189928

SCHEMBL4189928

CC(CC1CCCCC1)NCc1ccccc1NS(=O)(=O)c1ccc2c(c1)OCC(=O)N2

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PKM P14618 9/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MAPK1 P28482 1/20 0.44
TSHR P16473 1/20 0.42
KDM4E B2RXH2 1/20 0.42
TP53 P04637 2/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4197989 0.85 PKM (0.42) PKMSMN1; SMN2KDM4ETP53LMNA
SCHEMBL4201904 0.85 PKM (0.56) PKMSMN1; SMN2LMNAALDH1A1
SCHEMBL4190344 0.84 PKM (0.40) PKMSMN1; SMN2KDM4ETP53LMNA
SCHEMBL4185954 0.84 PKM (0.43) PKMSMN1; SMN2KDM4ETP53LMNA
SCHEMBL4202479 0.84 PKM (0.57) PKMSMN1; SMN2LMNAALDH1A1
SCHEMBL4193422 0.83 PKM (0.42) PKMSMN1; SMN2KDM4ETP53LMNA
SCHEMBL4202494 0.83 ATM (0.49) PKMKDM4ETP53LMNAALDH1A1
SCHEMBL4202599 0.82 ATM (0.49) PKMKDM4ETP53LMNA
SCHEMBL4204437 0.80 KDM4E (0.43) PKMSMN1; SMN2MAPK1TSHRKDM4E
SCHEMBL4188219 0.80 KDM4E (0.43) PKMSMN1; SMN2MAPK1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
CN-101203504-A Antimicrobial agents RANBAXY LAB LTD (IN) 2008-06-18 CN claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed
CN-101203504-A Antimicrobial agents RANBAXY LAB LTD (IN) 2008-06-18 CN disclosed
EP-1879877-A2 ANTIMICROBIAL AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-23 EP disclosed
WO-2006117762-A2 ANTIMICROBIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 PKM 1855/4885SMN1; SMN2 3369/4885MAPK1 4188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.