Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023313 | 0.92 | PTGES (0.40) | KDRNPC1TNFRAB9ANOD1 | |
| SCHEMBL4023999 | 0.92 | PPARD (0.38) | NR4A2NPC1TNFRAB9ANOD1 | |
| SCHEMBL4021877 | 0.79 | PTGES (0.46) | PTGESPPARDPPARA | |
| SCHEMBL5230129 | 0.78 | S1PR1 (0.37) | EPHX2CFTRMKNK1MKNK2MAPT | |
| SCHEMBL4026661 | 0.78 | F2RL3 (0.40) | CYP3A4PTGESMAPTPPARDPPARA | |
| SCHEMBL4021807 | 0.73 | PTGES (0.60) | PTGESPPARA | |
| Hydrochloric Acid SCHEMBL4021808 | 0.73 | PTGES (0.59) | PTGESPPARA | |
| SCHEMBL4024171 | 0.70 | PTGES (0.58) | CYP3A4CYP3A5PTGESPPARA | |
| SCHEMBL333599 | 0.68 | LMNA (0.50) | MAPTPPARA | |
| SCHEMBL3580289 | 0.67 | PTGES (0.43) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765775-B1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-04-29 | — | — | EP | disclosed |