SCHEMBL4190076

SCHEMBL4190076

CCCCCCN(CCCCC)S[C]=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 4/20 0.42
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.36
MGLL Q99685 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
S1PR2 O95136 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
S1PR5 Q9H228 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH4 P08319 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
GGPS1 O95749 3/20 0.32
GBA1 P04062 1/20 0.32
EPHX2 P34913 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2308384 0.98 DNM1 (0.41) DNM1TSHRTHRBMGLLCA12
SCHEMBL564627 0.98 DNM1 (0.39) DNM1TSHRTHRBMGLLCA12
SCHEMBL4438505 0.93 DNM1 (0.36) DNM1TSHRMGLL
SCHEMBL7497954 0.89 DNM1 (0.36) DNM1MGLL
SCHEMBL4203223 0.86 ALDH1A1 (0.31) TSHRCA12CA1CA9
SCHEMBL7803023 0.82 CA12 (0.33) MGLLCA12CA1CA9
SCHEMBL4199252 0.77 DNM1 (0.42) DNM1TSHRTHRBMGLLCA12
SCHEMBL7687639 0.76 DNM1 (0.36) DNM1MGLL
SCHEMBL14841879 0.72 DNM1 (0.52) DNM1TSHRTHRBMGLLCA12
SCHEMBL11366194 0.72 DNM1 (0.52) DNM1TSHRTHRBMGLLCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2027095-A1 HETEROAROYL-SUBSTITUTED ALANINES WITH A HERBICIDAL ACTION BASF SE (DE) 2009-02-25 EP disclosed
EP-2024327-A1 BENZOYL-SUBSTITUTED ALANINES BASF SE (DE) 2009-02-18 EP disclosed
WO-2007134984-A1 HETEROAROYL-SUBSTITUTED ALANINES WITH A HERBICIDAL ACTION BASF SE (DE) 2007-11-29 WO disclosed
WO-2007134971-A1 BENZOYL-SUBSTITUTED ALANINES BASF SE (DE) 2007-11-29 WO disclosed