SCHEMBL4199252

SCHEMBL4199252

CCCCCN(C)S[C]=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 5/20 0.42
S1PR2 O95136 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
S1PR5 Q9H228 1/20 0.34
GGPS1 O95749 4/20 0.32
EPHX2 P34913 1/20 0.32
FDPS P14324 1/20 0.32
AGTR1 P30556 1/20 0.32
OPRM1 P35372 1/20 0.32
PDE3A Q14432 1/20 0.32
MGLL Q99685 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH4 P08319 1/20 0.31
TSHR P16473 1/20 0.30
THRB P10828 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564627 0.79 DNM1 (0.39) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL4190076 0.77 DNM1 (0.42) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL4438505 0.76 DNM1 (0.36) DNM1MGLLTSHR
SCHEMBL2308384 0.76 DNM1 (0.41) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL7497954 0.76 DNM1 (0.36) DNM1MGLL
SCHEMBL24692609 0.73 DNM1 (0.48) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL7783867 0.69
SCHEMBL25698138 0.69
SCHEMBL271218 0.69
SCHEMBL4203223 0.68 ALDH1A1 (0.31) TSHRCA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2027095-A1 HETEROAROYL-SUBSTITUTED ALANINES WITH A HERBICIDAL ACTION BASF SE (DE) 2009-02-25 EP disclosed
EP-2024327-A1 BENZOYL-SUBSTITUTED ALANINES BASF SE (DE) 2009-02-18 EP disclosed
WO-2007134984-A1 HETEROAROYL-SUBSTITUTED ALANINES WITH A HERBICIDAL ACTION BASF SE (DE) 2007-11-29 WO disclosed
WO-2007134971-A1 BENZOYL-SUBSTITUTED ALANINES BASF SE (DE) 2007-11-29 WO disclosed