⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128499 | 0.79 | — | — | |
| SCHEMBL5144478 | 0.76 | ADORA2A (0.44) | — | |
| SCHEMBL1951056 | 0.76 | KMT2A (0.32) | — | |
| SCHEMBL24737984 | 0.68 | ALDH1A1 (0.36) | — | |
| SCHEMBL1128530 | 0.67 | PDE4A (0.38) | — | |
| SCHEMBL9006295 | 0.65 | MAOA (0.61) | — | |
| SCHEMBL7992255 | 0.65 | KDM4E (0.30) | — | |
| SCHEMBL2355969 | 0.65 | CYP1A2 (0.46) | — | |
| SCHEMBL561873 | 0.65 | PRMT5 (0.30) | — | |
| SCHEMBL30940151 | 0.64 | KMT2A (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024360-A2 | SUBSTITUTED PYRAZOLOPYRIMIDINES | Cephalon, Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2008063232-A2 | SUBSTITUTED PYRAZOLOPYRIMIDINES | CEPHALON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |