Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24737984 | 0.82 | ALDH1A1 (0.36) | KDM4E | |
| SCHEMBL25201791 | 0.68 | — | — | |
| SCHEMBL28088881 | 0.68 | ALDH1A1 (0.35) | CYP3A4 | |
| SCHEMBL27391188 | 0.67 | ALDH1A1 (0.35) | KDM4E | |
| SCHEMBL561873 | 0.67 | PRMT5 (0.30) | — | |
| SCHEMBL4693319 | 0.67 | LMNA (0.36) | CYP3A4 | |
| SCHEMBL4190372 | 0.65 | — | — | |
| SCHEMBL25103760 | 0.65 | CSNK2A1 (0.36) | — | |
| SCHEMBL24010728 | 0.65 | KDM4E (0.40) | KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL18260554 | 0.65 | POLB (0.47) | KDM4ECYP3A4CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025044946-A1 | COMPOUND ACTING AS MRGPRX2 ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2025-03-06 | — | — | WO | disclosed |
| CN-119504738-A | Compounds as MRGPRX2 antagonists, methods of preparation and use thereof | 武汉人福创新药物研发中心有限公司 | 2025-02-25 | — | — | CN | disclosed |
| WO-2001029045-A1 | GRAM-POSITIVE SELECTIVE ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 2001-04-26 | — | — | WO | disclosed |