SCHEMBL4190618

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4188479	0.86	CYP19A1 (0.53)	CYP19A1LMNACTSDBACE1BACE2
	SCHEMBL11079440	0.85	CYP19A1 (0.55)	CYP19A1CTSDBACE1PRMT5WDR77
	SCHEMBL4190208	0.75	CYP19A1 (0.62)	CYP19A1BACE1
	SCHEMBL4181298	0.73	CYP19A1 (0.59)	CYP19A1LMNABACE1
	SCHEMBL4184614	0.73	CYP19A1 (0.59)	CYP19A1CTSDBACE1BACE2REN
	SCHEMBL2779577	0.73	CYP19A1 (1.00)	CYP19A1
	SCHEMBL6002297	0.73	CYP19A1 (0.72)	CYP19A1BACE1ALDH1A1
	SCHEMBL11076987	0.73	CYP19A1 (0.72)	CYP19A1CTSDBACE1BACE2ALDH1A1
	SCHEMBL11078445	0.72	CYP19A1 (0.71)	CYP19A1CTSDBACE1PRMT5WDR77
	SCHEMBL4771129	0.72	CYP19A1 (0.58)	CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.