SCHEMBL4191120

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4187111	0.92	ICAM1 (0.43)	AKR1C2ICAM1SELEVCAM1KDM4E
	SCHEMBL4188868	0.83	PTGDR2 (0.41)	AKR1C2AKR1C3PTGS1TSHR
	SCHEMBL4479968	0.83	TSPO (0.39)	ICAM1SELEVCAM1KDM4ETSHR
	SCHEMBL4187113	0.82	ICAM1 (0.42)	ICAM1SELEVCAM1KDM4ELMNA
	SCHEMBL4195231	0.82	ICAM1 (0.42)	ICAM1SELEVCAM1KDM4ELMNA
	SCHEMBL4192779	0.81	ICAM1 (0.44)	ICAM1SELEVCAM1KDM4ELMNA
	SCHEMBL4187170	0.81	CYP1A2 (0.38)	ICAM1SELEVCAM1KDM4EHSD17B10
	SCHEMBL4478135	0.80	ICAM1 (0.41)	ICAM1SELEVCAM1KDM4ELMNA
	SCHEMBL4187007	0.80	ICAM1 (0.48)	ICAM1SELEVCAM1KDM4ELMNA
	SCHEMBL4180054	0.80	MCL1 (0.43)	KDM4EHSD17B10CYP2C9LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.