SCHEMBL4187170

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4472512	0.98	TSPO (0.36)	CYP1A2CYP3A4CYP2D6CYP2C19NPC1
	SCHEMBL4188725	0.96	CYP1A2 (0.43)	CYP1A2CYP3A4CYP2D6CYP2C19NPC1
	SCHEMBL4479968	0.94	TSPO (0.39)	NPC1RAB9AKDM4EALDH1A1ICAM1
	SCHEMBL4478135	0.87	ICAM1 (0.41)	NPC1RAB9AKDM4EALDH1A1LMNA
	SCHEMBL4191256	0.86	KDM4E (0.41)	CYP1A2CYP3A4CYP2C19KDM4EALDH1A1
	SCHEMBL4191228	0.86	PTGS2 (0.39)	NPC1RAB9AKDM4EALDH1A1LMNA
	SCHEMBL13762171	0.85	ALDH1A1 (0.35)	CYP1A2CYP3A4CYP2C19KDM4EALDH1A1
	SCHEMBL4198529	0.85	KDM4E (0.33)	NPC1RAB9AKDM4EALDH1A1LMNA
	SCHEMBL4193966	0.84	POLB (0.43)	CYP1A2CYP3A4CYP2C19KDM4EALDH1A1
	SCHEMBL4193967	0.84	MLYCD (0.38)	KDM4EALDH1A1ICAM1SELEVCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.