Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | F7 | P08709 | 3/20 | 0.38 |
| ▸ | F3 | P13726 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18813838 | 1.00 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4PPARA | |
| SCHEMBL4808522 | 0.86 | — | — | |
| SCHEMBL4808526 | 0.86 | — | — | |
| SCHEMBL4877054 | 0.86 | PPARA (0.58) | CHRNB2CHRNB4CHRNA3CHRNA4PPARA | |
| SCHEMBL4877044 | 0.86 | PPARA (0.58) | CHRNB2CHRNB4CHRNA3CHRNA4PPARA | |
| SCHEMBL24091341 | 0.82 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4PPARA | |
| SCHEMBL10580610 | 0.82 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4PPARA | |
| SCHEMBL10150427 | 0.82 | PPARA (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4PPARA | |
| SCHEMBL12252969 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL23139471 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8075937-B2 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-13 | — | — | US | disclosed |
| US-8075937-B2 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-13 | — | — | US | disclosed |
| US-8075937-B2 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-12-13 | — | — | US | disclosed |
| US-20090311402-A1 | ALKYLDIENAMIDES EXHIBITING TASTE AND SENSORY EFFECT IN FLAVOR COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-12-17 | — | — | US | disclosed |
| US-20090311402-A1 | ALKYLDIENAMIDES EXHIBITING TASTE AND SENSORY EFFECT IN FLAVOR COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-12-17 | — | — | US | disclosed |
| US-20090311402-A1 | ALKYLDIENAMIDES EXHIBITING TASTE AND SENSORY EFFECT IN FLAVOR COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-12-17 | — | — | US | disclosed |
| US-7632531-B2 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | International Flavors & Fragnances Inc. (US) | 2009-12-15 | — | — | US | disclosed |
| US-7632531-B2 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | International Flavors & Fragnances Inc. (US) | 2009-12-15 | — | — | US | disclosed |
| US-7632531-B2 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | International Flavors & Fragnances Inc. (US) | 2009-12-15 | — | — | US | disclosed |
| EP-1473287-B1 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | INT FLAVORS & FRAGRANCES INC (US) | 2006-06-21 | — | — | EP | disclosed |
| EP-1473287-A2 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2004-11-03 | — | — | EP | disclosed |
| US-20040202619-A1 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040202619-A1 | Alkyldienamides exhibiting taste and sensory effect in flavor compositions | TAS2R5, TAS2R4, TAS2R3 | CHRNB2 239/4885CHRNB4 95/4885CHRNA3 88/4885 |
| US-20090311402-A1 | ALKYLDIENAMIDES EXHIBITING TASTE AND SENSORY EFFECT IN FLAVOR COMPOSITIONS | TAS2R5, TAS2R45, TAS2R16 | CHRNB2 833/4885CHRNB4 477/4885CHRNA3 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.