Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.73 |
| ▸ | METAP1 | P53582 | 3/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28154653 | 0.92 | ACHE (0.63) | ACHEMETAP1PARP10PARP11HTR2A | |
| SCHEMBL2481939 | 0.85 | ACHE (1.00) | ACHEMETAP1PARP10HTR2AHTR2C | |
| SCHEMBL29893908 | 0.85 | ACHE (1.00) | ACHEMETAP1PARP10HTR2AHTR2C | |
| SCHEMBL12433392 | 0.81 | ACHE (0.54) | ACHEMETAP1PARP10PARP11 | |
| SCHEMBL569403 | 0.79 | ACHE (0.74) | ACHEHTR2AHTR2CHTR2B | |
| SCHEMBL14939019 | 0.79 | METAP1 (0.54) | ACHEMETAP1PARP10PARP11HTR2A | |
| SCHEMBL6972986 | 0.79 | METAP1 (0.54) | ACHEMETAP1PARP10PARP11HTR2A | |
| SCHEMBL1500072 | 0.79 | METAP1 (0.56) | ACHEMETAP1PARP10PARP11 | |
| SCHEMBL22012874 | 0.79 | METAP1 (0.56) | ACHEMETAP1PARP10PARP11 | |
| SCHEMBL29404958 | 0.79 | METAP1 (0.56) | ACHEMETAP1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022023460-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2022-02-03 | — | — | WO | disclosed |
| CN-107108445-B | Intermediate compounds for the production of perfuming ingredients | 弗门尼舍有限公司 | 2020-08-14 | — | — | CN | disclosed |
| EP-3245185-B1 | INTERMEDIATE COMPOUNDS FOR PRODUCING PERFUMING INGREDIENTS | FIRMENICH & CIE (CH) | 2019-03-13 | — | — | EP | disclosed |
| US-9981894-B2 | Intermediate compounds for producing perfuming ingredients | FIRMENICH SA (CH) | 2018-05-29 | — | — | US | disclosed |
| US-20180002260-A1 | INTERMEDIATE COMPOUNDS FOR PRODUCING PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2018-01-04 | — | — | US | disclosed |
| EP-3245185-A1 | INTERMEDIATE COMPOUNDS FOR PRODUCING PERFUMING INGREDIENTS | Firmenich SA (CH) | 2017-11-22 | — | — | EP | disclosed |
| CN-107108445-A | Midbody compound for producing perfuming component | 弗门尼舍有限公司 | 2017-08-29 | — | — | CN | disclosed |
| WO-2016113151-A1 | INTERMEDIATE COMPOUNDS FOR PRODUCING PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2016-07-21 | — | — | WO | disclosed |
| EP-1963347-B1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2011-10-19 | — | — | EP | disclosed |
| US-7550544-B2 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-06-23 | — | — | US | disclosed |
| EP-0508586-B1 | Substituted indenyl compounds | FGN INC (US) | 1995-05-31 | — | — | EP | disclosed |
| US-5401774-A | Treatment of potentially cancerous growths | UNIVERSITY OF ARIZONA (US) | 1995-03-28 | — | — | US | disclosed |
| US-5360936-A | Process for the preparation of substituted indanones | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-01 | — | — | US | disclosed |
| US-5329050-A | Process for the preparation of substituted indanones, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| EP-0587107-A1 | Process for the preparation of substituted indanones | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-16 | — | — | EP | disclosed |
| EP-0568879-A1 | Process for the preparation of substituted indanones and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-10 | — | — | EP | disclosed |
| EP-0508586-A1 | Substituted indenyl compounds | FGN, INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0181145-B1 | HETEROCYCLIC COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-01-31 | — | — | EP | disclosed |
| US-4755511-A | Tricyclic pyridazinone compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-07-05 | — | — | US | disclosed |
| EP-0181145-A2 | Heterocyclic compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180002260-A1 | INTERMEDIATE COMPOUNDS FOR PRODUCING PERFUMING INGREDIENTS | PTGIS, PTGES, POR | ACHE 423/4885METAP1 3109/4885PARP10 2170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.