Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.58 |
| ▸ | PRKCQ | Q04759 | 16/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4194236 | 0.83 | PRKCQ (0.52) | PRKCQPRKCD | |
| SCHEMBL4187943 | 0.83 | PRKCQ (0.66) | SRCPRKCQPRKCD | |
| SCHEMBL4190125 | 0.80 | PRKCQ (0.65) | PRKCQPRKCD | |
| SCHEMBL4240532 | 0.78 | PRKCQ (0.49) | PRKCQPRKCD | |
| SCHEMBL2974245 | 0.76 | PRKCQ (0.79) | PRKCQPRKCD | |
| SCHEMBL4245343 | 0.75 | PRKCQ (0.42) | PRKCQPRKCD | |
| SCHEMBL4247140 | 0.73 | PRKCQ (0.57) | PRKCQPRKCD | |
| SCHEMBL2978719 | 0.73 | PRKCQ (0.76) | PRKCQPRKCD | |
| SCHEMBL2986068 | 0.72 | PRKCQ (0.71) | PRKCQPRKCD | |
| SCHEMBL2972934 | 0.70 | PRKCQ (1.00) | PRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027093-A2 | SUBSTITUTED CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | Wyeth (US) | 2009-02-25 | — | — | EP | claimed |
| WO-2007146323-A2 | SUBSTITUTED CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH (US) | 2007-12-21 | — | — | WO | claimed |