Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 12/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4190125 | 0.77 | PRKCQ (0.65) | PRKCQPRKCD | |
| SCHEMBL4187943 | 0.76 | PRKCQ (0.66) | PRKCQPRKCD | |
| SCHEMBL2985905 | 0.75 | PRKCQ (0.64) | PRKCQPRKCD | |
| SCHEMBL4191870 | 0.75 | SRC (0.58) | PRKCQPRKCD | |
| SCHEMBL4194236 | 0.75 | PRKCQ (0.52) | PRKCQPRKCD | |
| SCHEMBL196440 | 0.73 | MGAM (0.55) | SMN1; SMN2HDAC4HDAC2HDAC8MAPT | |
| SCHEMBL17954514 | 0.72 | BCHE (0.41) | PGRARSMN1; SMN2MAPTMGAM | |
| SCHEMBL28434131 | 0.72 | MAPT (0.43) | PGRARSMN1; SMN2MAPTMGAM | |
| SCHEMBL5481376 | 0.72 | PRKCQ (0.45) | PRKCQPRKCDSMN1; SMN2 | |
| SCHEMBL28450869 | 0.71 | MAPT (0.40) | PGRARMAPTMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029543-A2 | SUBSTITUTED 3-CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | Wyeth (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007146376-A2 | SUBSTITUTED 3-CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH (US) | 2007-12-21 | — | — | WO | disclosed |