SCHEMBL4191886

SCHEMBL4191886

O=C(O)c1cc(N(Cl)c2ccccc2)c(C(=O)O)cc1N(Cl)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
ALOX15 P16050 1/20 0.44
NPSR1 Q6W5P4 2/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
HMGB1 P09429 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA7 P43166 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CA9 Q16790 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
CA14 Q9ULX7 1/20 0.39
POLB P06746 3/20 0.38
HTT P42858 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4249097 0.84 ALDH1A1 (0.50) ALDH1A1ALOX15NPSR1KMT2AKDM4E
SCHEMBL27763942 0.84 KDM4E (0.49) ALDH1A1ALOX15KMT2AMEN1KDM4E
SCHEMBL7811751 0.79 NPSR1 (0.48) ALDH1A1ALOX15NPSR1KMT2AKDM4E
SCHEMBL15309180 0.73 ALDH1A1 (0.43) ALDH1A1ALOX15NPSR1KMT2AMEN1
SCHEMBL29131039 0.73 TSHR (0.42) ALDH1A1ALOX15KMT2AHPGDNAPRT
SCHEMBL19596110 0.72 ALDH1A1 (0.44) ALDH1A1ALOX15KMT2AMEN1KDM4E
SCHEMBL7567279 0.72 MCL1 (0.41) ALDH1A1ALOX15NPSR1KMT2AMEN1
SCHEMBL8061910 0.69 ALDH1A1 (0.44) ALDH1A1ALOX15NPSR1KMT2AMEN1
SCHEMBL4070091 0.68 ALDH1A1 (0.56) ALDH1A1ALOX15KDM4EHPGDCA12
SCHEMBL2700283 0.68 ALDH1A1 (0.56) ALDH1A1ALOX15NPSR1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2024325-B1 2,5-DI(METHOXYANILINO)TEREPHTHALIC ACID POLYMORPHS AND QUINACRIDONES REALIZED THEREFROM SUN CHEMICAL CORP (US) 2017-05-03 EP disclosed
CN-101448780-B 2, 5-di (methoxyanilino) terephthalic acid polymorphs and quinacridones obtained therefrom SUN CHEMICAL CORP 2014-06-18 CN disclosed
US-8557990-B2 2,5-di(methoxyanilino) terephthalic acid polymorphs and quinacridones realized therefrom SUN CHEMICAL CORPORATION (US) 2013-10-15 US disclosed
US-20130053568-A1 2,5-DI(METHOXYANILINO) TEREPHTHALIC ACID POLYMORPHS AND QUINACRIDONES REALIZED THEREFROM2,5-DI(METHOXYANILINO) TEREPHTHALIC ACID POLYMORPHS AND QUINACRIDONES REALIZED THEREFROM PIGMENTS SERVICES, INC. 2013-02-28 US disclosed
US-20090186200-A1 2,5-DI(METHOXYANILINO) TEREPHTHALIC ACID POLYMORPHS AND QUINACRIDONES REALIZED THEREFROM SUN CHEMICAL CORPORATION 2009-07-23 US disclosed
EP-2024325-A1 2,5-DI(METHOXYANILINO)TEREPHTHALIC ACID POLYMORPHS AND QUINACRIDONES REALIZED THEREFROM Sun Chemical Corporation (US) 2009-02-18 EP disclosed
WO-2007139724-A1 2,5-DI(METHOXYANILINO)TEREPHTHALIC ACID POLYMORPHS AND QUINACRIDONES REALIZED THEREFROM SUN CHEMICAL CORPORATION (US) 2007-12-06 WO disclosed
EP-1334154-A2 PROCESS FOR MANUFACTURING PIGMENTARY QUINACRIDONES SUN CHEMICAL CORPORATION (US) 2003-08-13 EP disclosed
WO-2002038680-A2 PROCESS FOR MANUFACTURING PIGMENTARY QUINACRIDONES SUN CHEMICAL CORPORATION (US) 2002-05-16 WO disclosed