Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192699 | 0.93 | ALDH1A1 (0.34) | — | |
| SCHEMBL4190725 | 0.83 | DRD2 (0.33) | — | |
| SCHEMBL4185436 | 0.78 | TTR (0.35) | TTR | |
| SCHEMBL28526074 | 0.70 | MAPT (0.36) | HDAC8HDAC6 | |
| SCHEMBL4186127 | 0.70 | SNCA (0.33) | — | |
| SCHEMBL4185433 | 0.69 | TTR (0.35) | TTR | |
| SCHEMBL28095230 | 0.67 | ALDH1A1 (0.36) | TTR | |
| SCHEMBL20466635 | 0.67 | HDAC3 (0.46) | HDAC8HDAC6 | |
| SCHEMBL4178414 | 0.66 | PRNP (0.33) | — | |
| SCHEMBL4191633 | 0.66 | DRD2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611909-B1 | Acridinium compound for use in the concurrent detection of target analytes in immunoassays or nucleic acid assays | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2009-11-03 | — | — | US | disclosed |
| EP-1104405-B1 | NEAR INFRARED CHEMILUMINESCENT ACRIDINIUM COMPOUNDS AND USES THEREOF | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2009-02-18 | — | — | EP | disclosed |
| US-7083986-B2 | Near infrared chemiluminescent acridinium compounds and uses thereof | BAYER HEALTHCARE LLC (US) | 2006-08-01 | — | — | US | disclosed |
| US-20020076823-A1 | Near infrared chemiluminescent acridinium compounds and uses thereof | BAYER CORPORATION (US) | 2002-06-20 | — | — | US | disclosed |
| US-6355803-B1 | COMPOUND COMPRISING EXTENDED, COPLANAR, CONJUGATED SYSTEM, FORMED BY ATTACHMENT OF FUNCTIONAL GROUP COMPRISING AROMATIC RING AND ELECTRON-DONATING GROUP ON ACRIDINIUM NUCLEUS, WHICH MAINTAINS COPLANARITY DURING LIGHT EMISSION | BAYER CORPORATION | 2002-03-12 | — | — | US | disclosed |