Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192247 | 0.88 | TRPV1 (0.34) | POLBSMN1; SMN2TDP1CASP7BRCA1 | |
| SCHEMBL3944735 | 0.76 | HTR2A (0.39) | POLBSMN1; SMN2TDP1TSHRKMT2A | |
| SCHEMBL5525205 | 0.75 | NPSR1 (0.44) | POLBSMN1; SMN2CASP7BRCA1TSHR | |
| SCHEMBL3942636 | 0.75 | ALDH1A1 (0.38) | POLBSMN1; SMN2TDP1CASP7BRCA1 | |
| SCHEMBL5474300 | 0.72 | TSHR (0.41) | POLBSMN1; SMN2CASP7BRCA1TSHR | |
| SCHEMBL3944909 | 0.72 | AKR1C3 (0.36) | POLBSMN1; SMN2TDP1TSHRKMT2A | |
| SCHEMBL3951275 | 0.69 | PDE4A (0.37) | POLBSMN1; SMN2TDP1TSHRKMT2A | |
| SCHEMBL3946661 | 0.69 | KMT2A (0.33) | POLBSMN1; SMN2TDP1TSHRKMT2A | |
| SCHEMBL4162479 | 0.63 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL20302390 | 0.62 | CHRM4 (0.52) | SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019099-A1 | TETRASUBSTITUTED PYRIMIDINE DERIVATIVES FOR CONTROLLING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2009-02-12 | — | — | WO | disclosed |