Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205235 | 0.87 | SMN1; SMN2 (0.37) | HTR2AHTR2CHTR2BSMN1; SMN2POLB | |
| SCHEMBL3942636 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2POLBTDP1TSHRLMNA | |
| SCHEMBL3943563 | 0.76 | POLB (0.36) | SMN1; SMN2POLBTDP1TSHRLMNA | |
| SCHEMBL5526686 | 0.74 | NPSR1 (0.46) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL3944338 | 0.73 | LMNA (0.35) | HTR2AHTR2CHTR2BSMN1; SMN2POLB | |
| SCHEMBL3951275 | 0.71 | PDE4A (0.37) | SMN1; SMN2POLBTDP1TSHRLMNA | |
| SCHEMBL5473951 | 0.71 | LMNA (0.53) | SMN1; SMN2TSHRLMNAMAPTHTT | |
| SCHEMBL3944909 | 0.71 | AKR1C3 (0.36) | SMN1; SMN2POLBTDP1TSHRMAPT | |
| SCHEMBL3946666 | 0.70 | SMN1; SMN2 (0.32) | SMN1; SMN2POLBTDP1TSHRMAPT | |
| SCHEMBL3946661 | 0.70 | KMT2A (0.33) | SMN1; SMN2POLBTDP1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019099-A1 | TETRASUBSTITUTED PYRIMIDINE DERIVATIVES FOR CONTROLLING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2009-02-12 | — | — | WO | disclosed |