Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479782 | 0.96 | KMT2A (0.51) | KMT2AMEN1CCR2PKMALDH1A1 | |
| SCHEMBL3479904 | 0.92 | KMT2A (0.53) | KMT2AMEN1CCR2PKMALDH1A1 | |
| SCHEMBL3479848 | 0.88 | KMT2A (0.50) | KMT2AMEN1CCR2PKMALDH1A1 | |
| SCHEMBL4965617 | 0.85 | KMT2A (0.49) | KMT2AMEN1CCR2PKMALDH1A1 | |
| SCHEMBL5567876 | 0.85 | L3MBTL1 (0.44) | KMT2AMEN1CCR2PKMALDH1A1 | |
| SCHEMBL4965614 | 0.84 | KMT2A (0.49) | KMT2AMEN1CCR2PKMALDH1A1 | |
| SCHEMBL3479972 | 0.83 | KMT2A (0.52) | KMT2AMEN1CCR2PKMALDH1A1 | |
| SCHEMBL4966694 | 0.83 | MAPK9 (0.52) | KMT2AMEN1ALDH1A1MAPK9MAPK10 | |
| SCHEMBL7146589 | 0.81 | KMT2A (0.50) | KMT2AMEN1CCR2PKMALDH1A1 | |
| SCHEMBL3479998 | 0.80 | KMT2A (0.50) | KMT2AMEN1CCR2PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |