Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786679 | 0.88 | SMN1; SMN2 (0.59) | CA12CA1CA9SMN1; SMN2MEN1 | |
| SCHEMBL30839283 | 0.84 | SMN1; SMN2 (0.45) | CA12CA1CA9SMN1; SMN2MEN1 | |
| SCHEMBL24117660 | 0.82 | SMN1; SMN2 (0.48) | CA12CA1CA9SMN1; SMN2MEN1 | |
| SCHEMBL30511277 | 0.81 | SMN1; SMN2 (0.52) | CA12CA1CA9SMN1; SMN2MEN1 | |
| SCHEMBL6040035 | 0.81 | MEN1 (0.62) | CA12CA1CA9SMN1; SMN2MEN1 | |
| SCHEMBL27840293 | 0.80 | CA12 (0.56) | CA12CA1CA9SMN1; SMN2MEN1 | |
| SCHEMBL55421 | 0.80 | — | — | |
| SCHEMBL7328541 | 0.79 | SMN1; SMN2 (0.62) | CA12CA1CA9SMN1; SMN2MEN1 | |
| SCHEMBL15125184 | 0.79 | SMN1; SMN2 (0.50) | CA12CA1CA9SMN1; SMN2MEN1 | |
| SCHEMBL22234568 | 0.79 | CA12 (0.50) | CA12CA1CA9SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | claimed |
| US-8344025-B2 | Oxalic acid derivatives and use thereof as physiological cooling active ingredients | SYMRISE AG (DE) | 2013-01-01 | — | — | US | claimed |
| US-20090054520-A1 | OXALIC ACID DERIVATIVES AND USE THEREOF AS PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS | SYMRISE GMBH & CO. KG (DE) | 2009-02-26 | — | — | US | claimed |
| WO-2025060911-A1 | SUBSTITUTED PYRIDOTRIAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 成都奥睿药业有限公司 | 2025-03-27 | — | — | WO | disclosed |
| WO-2025001687-A1 | Α-KETO ACID AMIDE OR SUBSTITUTED OXALIC ACID AMIDE ESTER COMPOUND AND COMPOSITION THEREOF | 南京桦冠生物技术有限公司 | 2025-01-02 | — | — | WO | disclosed |
| CN-118878535-A | Substituted pyridotriazole compound, preparation method and application thereof | 成都奥睿药业有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-115403519-B | Synthesis method of N-substituted isonicotinamide compound driven by visible light | 河南师范大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-115521275-B | Method for preparing oxamide compounds by using gold-based catalyst | 中国科学院兰州化学物理研究所 | 2024-01-05 | — | — | CN | disclosed |
| CN-116554122-B | Alpha-keto acid amide or substituted oxalic acid amide ester compound and composition thereof | 南京桦冠生物技术有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116554122-A | Alpha-keto acid amide or substituted oxalic acid amide ester compound and composition thereof | 南京桦冠生物技术有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-115521275-A | Method for preparing oxamide compound by using gold-based catalyst | 中国科学院兰州化学物理研究所 | 2022-12-27 | — | — | CN | disclosed |
| EP-2391212-A1 | BRIDGED COMPOUNDS AS HIV INTEGRASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010088167-A1 | BRIDGED COMPOUNDS AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-08-05 | — | — | WO | disclosed |
| CN-101646674-A | The indoles and the benzoazepine derivative that are used for the treatment of hepatitis C | SQUIBB BRISTOL MYERS CO US | 2010-02-10 | — | — | CN | disclosed |
| EP-2114947-A1 | INDOLOBENZAZEPINE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | Brystol-Myers Squibb Company (US) | 2009-11-11 | — | — | EP | disclosed |
| US-7541352-B2 | Compounds for the treatment of hepatitis C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-06-02 | — | — | US | disclosed |
| US-20090054520-A1 | OXALIC ACID DERIVATIVES AND USE THEREOF AS PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS | SYMRISE GMBH & CO. KG (DE) | 2009-02-26 | — | — | US | disclosed |
| WO-2008097796-A1 | INDOLOBENZAZEPINE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-08-14 | — | — | WO | disclosed |
| US-20080188458-A1 | Compounds for the Treatment of Hepatitis C | BRISTOL-MYERS SQUIBB COMPANY | 2008-08-07 | — | — | US | disclosed |
| US-4022765-A | ANTI-INFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188458-A1 | Compounds for the Treatment of Hepatitis C | HAVCR2, HCCS, SLC10A1 | CA12 1778/4885CA1 4401/4885CA9 2697/4885 |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | CA12 2758/4885CA1 1069/4885CA9 2359/4885 |
| US-20090054520-A1 | OXALIC ACID DERIVATIVES AND USE THEREOF AS PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS | OTC, OAT, HOGA1 | CA12 23/4885CA1 5/4885CA9 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.