SCHEMBL4192842

SCHEMBL4192842

CC12CCCC(C)(O1)C1CC(C)(C)C1CC2

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.54
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
RECQL P46063 1/20 0.36
FTH1 P02794 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,7-Epoxycaryophyllan-6-Ol SCHEMBL24176170 0.70 CYP3A4 (1.00) CYP3A4ALDH1A1FTH1CYP2C9CYP2C19
3,7-Epoxycaryophyllan-6-Ol SCHEMBL24176356 0.70 CYP3A4 (1.00) CYP3A4ALDH1A1FTH1CYP2C9CYP2C19
SCHEMBL4274557 0.69 CYP3A4 (0.57) CYP3A4ALDH1A1LMNAMAPTTSHR
SCHEMBL4272327 0.66 CYP3A4 (0.41) CYP3A4ALDH1A1LMNAMAPTTSHR
SCHEMBL10774216 0.64 CYP3A4 (0.39) CYP3A4
SCHEMBL24474355 0.64 LMNA (0.41) LMNAMAPTTSHRMAPK1RECQL
SCHEMBL19973096 0.60 CYP3A4 (0.42) CYP3A4ALDH1A1LMNAMAPTFTH1
Beta-Caryophyllene Alcohol SCHEMBL22108417 0.59 ALDH1A1 (1.00) CYP3A4ALDH1A1LMNAMAPT
Beta-Caryophyllene Alcohol SCHEMBL17627671 0.59 ALDH1A1 (1.00) CYP3A4ALDH1A1LMNAMAPT
Beta-Caryophyllene Alcohol SCHEMBL3508459 0.59 ALDH1A1 (1.00) CYP3A4ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090197949-A1 ANTITUMOR METHODS AND COMPOSITIONS COMPRISING SESQUITERPENE DERIVATIVES F.P.L. PHARMA, INC. (CA) 2009-08-06 US disclosed
US-20040191342-A1 Antitumor methods and compositions comprising sesquiterpene derivatives F.P.L. PHARMA INC. (CA) 2004-09-30 US disclosed
EP-1372677-A1 ANTITUMOR METHODS AND COMPOSITIONS COMPRISING SESQUITERPENE DERIVATIVES F.P.L. Pharma Inc. (CA) 2004-01-02 EP disclosed
WO-2002078719-A1 ANTITUMOR METHODS AND COMPOSITIONS COMPRISING SESQUITERPENE DERIVATIVES F.P.L. PHARMA INC. (CA) 2002-10-10 WO disclosed