Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | FTH1 | P02794 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13057404 | 0.75 | F10 (0.36) | CYP3A4LMNAMAPTF10 | |
| SCHEMBL24524173 | 0.61 | CYP3A4 (0.33) | CYP3A4ALDH1A1USP2LMNAMAPT | |
| 3,7-Epoxycaryophyllan-6-Ol SCHEMBL24176170 | 0.60 | CYP3A4 (1.00) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| 3,7-Epoxycaryophyllan-6-Ol SCHEMBL24176356 | 0.60 | CYP3A4 (1.00) | CYP3A4ALDH1A1FTH1CYP2C9CYP2C19 | |
| SCHEMBL4272327 | 0.59 | CYP3A4 (0.41) | CYP3A4ALDH1A1USP2LMNAMAPT | |
| SCHEMBL17857876 | 0.59 | ALDH1A1 (0.39) | CYP3A4ALDH1A1USP2LMNAMAPT | |
| SCHEMBL11224933 | 0.58 | CYP3A4 (0.33) | CYP3A4 | |
| SCHEMBL9618702 | 0.57 | ACHE (0.32) | F10 | |
| SCHEMBL21475407 | 0.56 | CYP3A4 (0.34) | CYP3A4MAPT | |
| SCHEMBL9589095 | 0.56 | TP53 (0.39) | CYP3A4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376041-A1 | METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-11-14 | — | — | US | disclosed |
| US-12098115-B2 | Methods and compositions for terpenoid synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2024-09-24 | — | — | US | disclosed |
| US-11952327-B2 | Methods and compositions for terpenoid synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2024-04-09 | — | — | US | disclosed |
| US-20240025843-A1 | METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20190270700-A1 | METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS | UNIV FLORIDA (US) | 2019-09-05 | — | — | US | disclosed |
| WO-2018053322-A1 | METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11952327-B2 | Methods and compositions for terpenoid synthesis | SQLE, GGPS1, LSS | CYP3A4 11/4885ALDH1A1 1162/4885USP2 3951/4885 |
| US-20240376041-A1 | METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS | SQLE, GGPS1, LSS | CYP3A4 11/4885ALDH1A1 1162/4885USP2 3951/4885 |
| US-20240025843-A1 | METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS | SQLE, GGPS1, LSS | CYP3A4 11/4885ALDH1A1 1162/4885USP2 3951/4885 |
| US-12098115-B2 | Methods and compositions for terpenoid synthesis | SQLE, GGPS1, LSS | CYP3A4 11/4885ALDH1A1 1162/4885USP2 3951/4885 |
| US-20190270700-A1 | METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS | SQLE, GGPS1, LSS | CYP3A4 11/4885ALDH1A1 1353/4885USP2 4005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.