SCHEMBL419343

SCHEMBL419343

Cc1ccc(I)cc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30337397 1.00
SCHEMBL1049725 0.81
SCHEMBL30176409 0.81
SCHEMBL19371787 0.78 ENPP2 (0.48)
SCHEMBL8269245 0.77 CYP1A2 (0.33)
SCHEMBL8236729 0.75 RXRA (0.37)
SCHEMBL78699 0.75
SCHEMBL29481423 0.75
SCHEMBL80458 0.75
SCHEMBL29455233 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3897833-B1 INHIBITORS OF APOL1 AND METHODS OF USING SAME VERTEX PHARMA (US) 2026-02-04 EP disclosed
US-20260008782-A1 HYDANTOIN MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYELINATION CONVELO THERAPEUTICS, INC. 2026-01-08 US disclosed
US-12509987-B2 Continuous characterization and communication of chemical tracer Patina IP LLC (US) 2025-12-30 US disclosed
WO-2025106383-A1 PYRROLIDINYL DERIVATIVES USEFUL AS HCN1/HCN 2 MODULATORS MERCK SHARP & DOHME LLC (US) 2025-05-22 WO disclosed
CN-119998288-A Hydantoin modulators of cholesterol biosynthesis and their use for promoting remyelination 基因泰克公司 2025-05-13 CN disclosed
US-RE50267-E1 Modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2025-01-14 US disclosed
US-20250009693-A1 MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. 2025-01-09 US disclosed
US-12186313-B2 Pyridazinone compounds and their use as DAAO inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-01-07 US disclosed
WO-2024073658-A1 HYDANTOIN MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYELINATION GENENTECH, INC. (US) 2024-04-04 WO disclosed
WO-2024058815-A1 CONTINUOUS CHARACTERIZATION AND COMMUNICATION OF CHEMICAL TRACER Patina IP LLC (US) 2024-03-21 WO disclosed
EP-0533267-A1 Benzanilide derivatives as 5-HT1D antagonists GLAXO GROUP LIMITED (GB) 1993-03-24 EP disclosed
EP-0518636-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-16 EP disclosed
EP-0409634-A2 Liquid crystal compounds and optically active compounds SANYO CHEMICAL INDUSTRIES LTD. (JP) 1991-01-23 EP disclosed
US-4889859-A ANTITUMOR AGENTS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 1989-12-26 US disclosed
EP-0327190-A1 Pyrido(2,3-d)pyrimidine derivatives THE TRUSTEES OF PRINCETON UNIVERSITY (US) 1989-08-09 EP disclosed
US-4161607-A Thermally stable, rigid bisphenols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-07-17 US disclosed
US-4107444-A INTERMEDIATES FOR POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-08-15 US disclosed
US-4096341-A MONOMERS FOR POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-06-20 US disclosed
US-4085091-A Thermally stable, rigid polyesters from thermally stable, rigid dibasic acids and aromatic dihydroxy compounds E. I. DUPONT DE NEMOURS AND COMPANY (US) 1978-04-18 US disclosed
US-4065432-A Thermally stable, rigid polyesters from aromatic dibasic acids and thermally stable, rigid bisphenols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-12-27 US disclosed