Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18245733 | 0.73 | TSHR (0.44) | CYP1A2GABRA1GABRB2ABCB11ALDH1A1 | |
| SCHEMBL18245123 | 0.66 | CYP3A4 (0.43) | HIF1ACYP1A2GABRA1GABRB2ABCB11 | |
| SCHEMBL7475089 | 0.66 | MIF (0.42) | OPRD1SMN1; SMN2HIF1ACYP1A2ABCB11 | |
| SCHEMBL6226870 | 0.62 | TSHR (0.53) | CYP1A2GABRA1GABRB2ABCB11ALDH1A1 | |
| SCHEMBL18245566 | 0.61 | TSHR (0.47) | — | |
| SCHEMBL27644155 | 0.61 | TSHR (0.51) | SMN1; SMN2HIF1ACYP1A2GABRA1GABRB2 | |
| SCHEMBL1022343 | 0.61 | ALDH1A1 (0.47) | HIF1ACYP1A2GABRA1GABRB2ABCB11 | |
| SCHEMBL330977 | 0.60 | GABRA1 (0.43) | HIF1ACYP1A2GABRA1GABRB2ABCB11 | |
| SCHEMBL7458733 | 0.59 | ALDH1A1 (0.38) | OPRD1CYP1A2ABCB11ALDH1A1NR3C1 | |
| SCHEMBL6889217 | 0.59 | MIF (0.47) | OPRD1CYP1A2GABRA1GABRB2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497904-B2 | METHODS AND TRANSGENIC PLANTS FOR THE PRODUCTION OF PLANT-PRODUCED GLYCOPOLYPEPTIDE MULTIMERS | SCRIPPS RESEARCH INST (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-1048734-B1 | Method for producing plants containing glycopolypeptide multimers, eg immunoglobulins | SCRIPPS RESEARCH INST (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7282625-B2 | Method of producing single chain protein in plant cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-10-16 | — | — | US | disclosed |
| US-7101688-B2 | Method of producing heteromultimeric mammalian proteins in plants | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-09-05 | — | — | US | disclosed |
| US-7037722-B1 | Transgenic plants expressing assembled secretory antibodies | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-05-02 | — | — | US | disclosed |
| US-7005560-B1 | Transgenic plants expressing assembled secretory antibodies | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-02-28 | — | — | US | disclosed |
| US-6995014-B1 | Transgenic plants expressing assembled secretory antibodies | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-02-07 | — | — | US | disclosed |
| US-20050241023-A1 | Transgenic plants expressing assembled secretory antibodies | THE SCRIPPS RESEARCH INSTITUTE | 2005-10-27 | — | — | US | disclosed |
| US-6852319-B2 | Method of use of transgenic plant expressed antibodies | THE SCRIPPS RESEARCH INSTITUE (US) | 2005-02-08 | — | — | US | disclosed |
| US-20030172407-A1 | Method of producing single chain protein in plant cells | THE SCRIPPS RESEARCH INSTITUTE | 2003-09-11 | — | — | US | disclosed |
| EP-1048734-A2 | Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins, and their use | The Scripps Research Institute (US) | 2000-11-02 | — | — | EP | disclosed |
| EP-0946717-A4 | — | — | 1999-11-17 | — | — | EP | disclosed |
| EP-0946717-A1 | TRANSGENIC PLANTS EXPRESSING ASSEMBLED SECRETORY ANTIBODIES | The Scripps Research Institute (US) | 1999-10-06 | — | — | EP | disclosed |
| US-5959177-A | Transgenic plants expressing assembled secretory antibodies | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-09-28 | — | — | US | disclosed |
| WO-1997042313-A1 | TRANSGENIC PLANTS EXPRESSING ASSEMBLED SECRETORY ANTIBODIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-11-13 | — | — | WO | disclosed |
| US-5639947-A | GENETIC ENGINEERING | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-06-17 | — | — | US | disclosed |
| US-5202422-A | Genetic engineered | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0497904-A4 | COMPOSITIONS CONTAINING PLANT-PRODUCED GLYCOPOLYPEPTIDE MULTIMERS, MULTIMERIC PROTEINS, AND THEIR USE | — | 1992-12-09 | — | — | EP | disclosed |
| EP-0497904-A1 | COMPOSITIONS CONTAINING PLANT-PRODUCED GLYCOPOLYPEPTIDE MULTIMERS AND METHODS FOR THEIR PRODUCTION | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991006320-A1 | COMPOSITIONS CONTAINING PLANT-PRODUCED GLYCOPOLYPEPTIDE MULTIMERS, MULTIMERIC PROTEINS, AND THEIR USE | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1991-05-16 | — | — | WO | disclosed |