Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | MMP16 | P51512 | 2/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114086 | 0.79 | PTGS2 (0.44) | ALDH1A1POLBMMP2MMP9MMP8 | |
| SCHEMBL1022343 | 0.78 | ALDH1A1 (0.47) | MIFALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL6889217 | 0.76 | MIF (0.47) | MIFALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL2204495 | 0.75 | PTGS2 (0.56) | ALDH1A1POLBMMP2MMP9MMP8 | |
| SCHEMBL3387728 | 0.75 | CXCL8 (0.41) | ALDH1A1MMP2MMP9MMP8MMP12 | |
| SCHEMBL6226870 | 0.72 | TSHR (0.53) | MIFALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL10622769 | 0.72 | HSD17B10 (0.38) | MIFMMP2MMP9MMP8MMP12 | |
| SCHEMBL1343676 | 0.70 | PTGS2 (0.50) | ALDH1A1MMP2MMP9MMP8MMP12 | |
| SCHEMBL18797642 | 0.70 | PTGS2 (0.50) | ALDH1A1POLBMMP2MMP9MMP8 | |
| SCHEMBL1110888 | 0.69 | ALDH1A1 (0.50) | MIFALDH1A1POLBMMP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551048-B1 | 2-imidazoline-5-one and 2-imidazoline-5-thiones derivatives as fungizides | AVENTIS CROPSCIENCE SA (FR) | 2002-08-07 | — | — | EP | disclosed |
| EP-0629616-B1 | Optically active 2-imidazolin-5-one derivatives as fungicides | AVENTIS CROPSCIENCE SA (FR) | 2001-08-29 | — | — | EP | disclosed |
| EP-0773720-B1 | FUNGICIDAL COMPOSITION INCLUDING A 2-IMIDAZOLINE-5-ONE | AVENTIS CROPSCIENCE SA (FR) | 2000-10-18 | — | — | EP | disclosed |
| EP-0773720-A1 | FUNGICIDAL COMPOSITION INCLUDING A 2-IMIDAZOLINE-5-ONE | RHONE-POULENC AGROCHIMIE (FR) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003044-A1 | FUNGICIDAL COMPOSITION INCLUDING A 2-IMIDAZOLINE-5-ONE | RHONE POULENC AGROCHIMIE (FR) | 1996-02-08 | — | — | WO | disclosed |
| EP-0629616-A2 | Optically aktive 2-imidazolin-5-one and 2-imidazolin-5-thione derivatives as fungicides | RHONE-POULENC AGROCHIMIE (FR) | 1994-12-21 | — | — | EP | disclosed |
| EP-0551048-A1 | 2-imidazoline-5-one and 2-imidazoline-5-thiones derivatives as fungizides | RHONE-POULENC AGROCHIMIE (FR) | 1993-07-14 | — | — | EP | disclosed |