SCHEMBL4193899

SCHEMBL4193899

CC(CC1CCCCCC1)NCc1ccccc1NS(=O)(=O)c1ccc(F)cc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 4/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
GAA P10253 1/20 0.47
POLB P06746 2/20 0.45
LMNA P02545 2/20 0.45
MCOLN3 Q8TDD5 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TSHR P16473 2/20 0.43
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
SLC16A3 O15427 1/20 0.41
ATM Q13315 1/20 0.40
USP30 Q70CQ3 1/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12050344 0.91 KDM4E (0.55) PKMKDM4EALDH1A1MEN1KMT2A
SCHEMBL4184516 0.90 KDM4E (0.53) PKMKDM4EALDH1A1MEN1KMT2A
SCHEMBL4202174 0.90 KDM4E (0.53) PKMKDM4EALDH1A1MEN1KMT2A
SCHEMBL4199567 0.88 KDM4E (0.52) PKMKDM4EALDH1A1MEN1KMT2A
SCHEMBL4194586 0.88 KDM4E (0.52) PKMKDM4EALDH1A1MEN1KMT2A
SCHEMBL4192565 0.88 KDM4E (0.47) PKMKDM4EALDH1A1MEN1KMT2A
SCHEMBL4187979 0.88 KDM4E (0.52) PKMKDM4EALDH1A1MEN1KMT2A
SCHEMBL4190400 0.88 KDM4E (0.52) PKMKDM4EALDH1A1MEN1KMT2A
SCHEMBL4188316 0.87 KDM4E (0.51) PKMKDM4EALDH1A1MEN1KMT2A
SCHEMBL12050329 0.87 PKM (0.51) PKMKDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed
EP-1879877-A2 ANTIMICROBIAL AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-23 EP disclosed
WO-2006117762-A2 ANTIMICROBIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 PKM 1855/4885KDM4E 3328/4885ALDH1A1 2744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.