SCHEMBL6740109

SCHEMBL6740109

Cc1c(F)c(F)c(F)c(C=O)c1F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
VCP P55072 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8136053 0.95 TAS1R3 (0.30)
SCHEMBL10482474 0.89 KDM4E (0.31)
SCHEMBL25863096 0.86 KDM4E (0.34)
SCHEMBL28273383 0.84
SCHEMBL419449 0.83 VCP (0.38) VCP
SCHEMBL1808857 0.80 VCP (0.36) VCP
SCHEMBL809345 0.80 VCP (0.33) VCP
SCHEMBL709843 0.78
SCHEMBL4661386 0.78 IGF1R (0.36)
SCHEMBL2559194 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210238139-A1 MODULATORS OF TRYPTOPHAN CATABOLISM E-THERAPEUTICS PLC (GB) 2021-08-05 US disclosed
EP-1801108-B9 MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS MITSUBISHI TANABE PHARMA CORP (JP) 2013-11-20 EP disclosed
EP-1801108-B1 MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS MITSUBISHI TANABE PHARMA CORP (JP) 2012-11-14 EP disclosed
US-6828467-B2 Industrial process of the hydrogenolysis of one hydroxyl or methanol group of a fluorinated benzenedimethanol carried out in a solvent in the presence of a catalyst; 2,3,5,6-tetra-fluorobenzyl alcohol from the 4-methyl derivative SHOWA DENKO K.K. (JP) 2004-12-07 US disclosed
EP-1322584-B1 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL SHOWA DENKO KK (JP) 2004-11-24 EP disclosed
US-20040010167-A1 Process for producing fluorinated methyl-benzyl alcohol SHOWA DENKO K.K. (JP) 2004-01-15 US disclosed
EP-1322584-A2 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL Showa Denko K.K. (JP) 2003-07-02 EP disclosed
WO-2002026678-A2 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL SHOWA DENKO K.K. (JP) 2002-04-04 WO disclosed
US-4551546-A INSECTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-11-05 US disclosed
US-4429153-A INSECTICIDES, MITICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-31 US disclosed
EP-0031199-B1 SUBSTITUTED BENZYL ESTERS OF CYCLOPROPANE CARBOXYLIC ACIDS AND THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND METHODS OF COMBATING INSECT PESTS THEREWITH, AND SUBSTITUTED BENZYL ALCOHOLS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-12-14 EP disclosed
US-4405640-A Substituted fluorobenzyl cyclopropane carboxylates useful as insecticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-09-20 US disclosed
EP-0060617-A1 Fluorobenzyl cyclopropane carboxylates, their preparation, compositions and use as insecticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-09-22 EP disclosed
EP-0031199-A1 Substituted benzyl esters of cyclopropane carboxylic acids and their preparation, compositions containing them and methods of combating insect pests therewith, and substituted benzyl alcohols IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210238139-A1 MODULATORS OF TRYPTOPHAN CATABOLISM TPH1, KYNU, TPH2 VCP 3384/4885
US-20040010167-A1 Process for producing fluorinated methyl-benzyl alcohol ADH1C, ADH5, ADH1A VCP 1400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.