SCHEMBL419468

SCHEMBL419468

C=Cc1[c]nccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL745255 0.76
SCHEMBL16289693 0.71
SCHEMBL5576077 0.70 CYP11B1 (0.48)
SCHEMBL305255 0.69
SCHEMBL959376 0.67
SCHEMBL299910 0.67
SCHEMBL1200601 0.66 CYP11B1 (0.58)
SCHEMBL4909130 0.66
SCHEMBL3260107 0.65 ALDH1A1 (0.37)
SCHEMBL3915149 0.64 TLR8 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 711 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115210270-B Film and use thereof 富士胶片制造欧洲有限公司 2024-06-04 CN claimed
US-20230107868-A1 Membranes and Their Uses FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2023-04-06 US claimed
WO-2021198419-A1 MEMBRANES AND THEIR USES FUJIFILM MANUFACTURING EUROPE BV (NL) 2021-10-07 WO claimed
EP-2714041-B1 ARYLOXYMETHYL CYCLOPROPANE DERIVATIVES AS PDE10 INHIBITORS MERCK SHARP & DOHME (US) 2016-10-19 EP claimed
US-8975261-B2 Aryloxmethyl cyclopropane derivatives as PDE10 inhibitors MERCK SHARP & DOHME CORP. (US) 2015-03-10 US claimed
US-20140336195-A1 ARYLOXMETHYL CYCLOPROPANE DERIVATIVES AS PDE10 INHIBITORS MERCK SHARP & DOHME LLC 2014-11-13 US claimed
WO-2012162213-A1 ARYLOXYMETHYL CYCLOPROPANE DERIVATIVES AS PDE10 INHIBITORS MERCK SHARP & DOHME CORP. (US) 2012-11-29 WO claimed
US-20100160574-A1 Polymerisation Using Chain Transfer Agents THE UNIVERSITY OF LEEDS (GB) 2010-06-24 US claimed
US-20090215965-A1 POLYMERISATION USING CHAIN TRANSFER AGENTS THE UNIVERSITY OF LEEDS (GB) 2009-08-27 US claimed
US-20070299221-A1 Polymerisation Using Chain Transfer Agents UNIVERSITY OF LEEDS, THE (GB) 2007-12-27 US claimed
EP-1147111-A1 CRYPTATE COMPOUNDS AND METHODS FOR DIAGNOSIS AND THERAPY AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) 2001-10-24 EP claimed
WO-2000040585-A1 CRYPTATE COMPOUNDS AND METHODS FOR DIAGNOSIS AND THERAPY AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) 2000-07-13 WO claimed
EP-0672094-B1 HYDROPHILIC POLYOXYETHYLENE PRESSURE SENSITIVE ADHESIVES MINNESOTA MINING & MFG (US) 1997-09-24 EP claimed
EP-0576544-B1 RADIATION-CURABLE ACRYLATE/SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS MINNESOTA MINING & MFG (US) 1997-06-04 EP claimed
US-5489624-A BASED ON NETWORKS OF TELECHELIC POLYOXYETHYLENE GLYCOL HAVING END GROUPS OF ETHYLENICALLY UNSATURATED FUNCTIONALITY; FOR BIOMEDICAL ELECTRODES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-02-06 US claimed
US-5484893-A ANTIBODIES CELLTECH LIMITED (GB) 1996-01-16 US claimed
EP-0672094-A1 HYDROPHILIC POLYOXYETHYLENE PRESSURE SENSITIVE ADHESIVES. MINNESOTA MINING & MFG (US) 1995-09-20 EP claimed
WO-1994012585-A1 HYDROPHILIC POLYOXYETHYLENE PRESSURE SENSITIVE ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-09 WO claimed
US-5247077-A Tri-aza macrocycles and processes for their preparation CELLTECH LIMITED (GB) 1993-09-21 US claimed
US-5247075-A Imaging agents, cytotoxic agents CELLTECH LIMITED (GB) 1993-09-21 US claimed