Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 3/20 | 0.57 |
| ▸ | PYGM | P11217 | 3/20 | 0.47 |
| ▸ | TYMP | P19971 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204364 | 0.92 | TK2 (0.54) | TK2PYGMTYMP | |
| SCHEMBL7182936 | 0.90 | TK2 (0.67) | TK2PYGMTYMPALDH1A1LMNA | |
| SCHEMBL1021637 | 0.90 | TK2 (0.67) | TK2PYGMTYMPALDH1A1LMNA | |
| SCHEMBL20875706 | 0.90 | TK2 (0.67) | TK2PYGMTYMPALDH1A1LMNA | |
| SCHEMBL22992480 | 0.90 | TK2 (0.67) | TK2PYGMTYMPALDH1A1LMNA | |
| SCHEMBL22992424 | 0.90 | TK2 (0.67) | TK2PYGMTYMPALDH1A1LMNA | |
| SCHEMBL62322 | 0.90 | TK2 (0.67) | TK2PYGMTYMPALDH1A1LMNA | |
| SCHEMBL62321 | 0.90 | TK2 (0.67) | TK2PYGMTYMPALDH1A1LMNA | |
| SCHEMBL4192644 | 0.90 | P2RY6 (0.51) | TK2PYGMLMNA | |
| SCHEMBL29509957 | 0.89 | TK2 (0.66) | TK2PYGMTYMPALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608402-B2 | DNA methylation specific signal amplification | LI WEIWEI | 2009-10-27 | — | — | US | disclosed |
| US-20090181373-A1 | DNA methylation specific signal amplification | LI WEIWEI | 2009-07-16 | — | — | US | disclosed |