SCHEMBL4194922

SCHEMBL4194922

CCCc1ccc(C=CC(=O)Oc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.57
THRB P10828 1/20 0.55
AKR1B10 O60218 4/20 0.52
AKR1B1 P15121 4/20 0.52
MAOB P27338 1/20 0.51
HTR1A P08908 1/20 0.51
CA12 O43570 2/20 0.48
CA4 P22748 2/20 0.48
CA6 P23280 2/20 0.48
CA5A P35218 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
CA5B Q9Y2D0 2/20 0.48
CA1 P00915 1/20 0.48
MET P08581 1/20 0.48
LMNA P02545 1/20 0.48
TRPM8 Q7Z2W7 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MITF O75030 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648890 0.88 KMT2A (0.60) KMT2AAKR1B10AKR1B1MAOBHTR1A
SCHEMBL11584765 0.84 THRB (0.60) KMT2ATHRBAKR1B10AKR1B1CA12
SCHEMBL11584769 0.84 THRB (0.60) KMT2ATHRBAKR1B10AKR1B1CA12
SCHEMBL29070316 0.83 KMT2A (0.55) KMT2AAKR1B10AKR1B1MAOBHTR1A
SCHEMBL29070314 0.83 KMT2A (0.55) KMT2AAKR1B10AKR1B1MAOBHTR1A
SCHEMBL11767686 0.82 THRB (0.52) KMT2ATHRBMAOBCA12CA4
SCHEMBL11767692 0.82 THRB (0.52) KMT2ATHRBMAOBCA12CA4
SCHEMBL15969787 0.81 KMT2A (0.60) KMT2ANPC1MAPTRAB9A
Phenyl Cinnamate SCHEMBL1055160 0.81 KMT2A (0.77) KMT2AAKR1B10AKR1B1MAOBHTR1A
Phenyl Cinnamate SCHEMBL1055161 0.81 KMT2A (0.77) KMT2AAKR1B10AKR1B1MAOBHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5092349-A Cigarette quality assurance method R. J. REYNOLDS TOBACCO COMPANY (US) 1992-03-03 US claimed
US-20090010958-A1 Compositions effective in altering the perception of malodor PATUS LTD. (IL) 2009-01-08 US disclosed
EP-1781239-A2 COMPOSITIONS EFFECTIVE IN ALTERING THE PERCEPTION OF MALODOR Patus Ltd (IL) 2007-05-09 EP disclosed
US-20070065394-A1 Compositions effective in altering the perception of malodor PATUS LTD. (IL) 2007-03-22 US disclosed
WO-2005046632-A9 COMPOSITIONS EFFECTIVE IN ALTERING THE PERCEPTION OF MALODOR PATUS LTD (IL) 2005-09-22 WO disclosed
WO-2005046632-A2 COMPOSITIONS EFFECTIVE IN ALTERING THE PERCEPTION OF MALODOR PATUS LTD. (IL) 2005-05-26 WO disclosed
US-5092349-A Cigarette quality assurance method R. J. REYNOLDS TOBACCO COMPANY (US) 1992-03-03 US disclosed