Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2882073 | 0.80 | ADORA2A (0.57) | KDM4EMEN1ALDH1A1POLBKMT2A | |
| SCHEMBL4189642 | 0.79 | PIM1 (0.56) | NPC1HPGDRAB9APIK3CDPIK3CA | |
| SCHEMBL4189638 | 0.79 | PIM1 (0.56) | NPC1HPGDRAB9APIK3CDPIK3CA | |
| SCHEMBL4189640 | 0.79 | PIM1 (0.56) | NPC1HPGDRAB9APIK3CDPIK3CA | |
| SCHEMBL4185899 | 0.76 | RIPK2 (0.38) | KDM4EMEN1ALDH1A1POLBKMT2A | |
| SCHEMBL4201167 | 0.75 | ERN1 (0.40) | ERN1KDM4EMEN1ALDH1A1POLB | |
| SCHEMBL29374061 | 0.74 | ADORA2A (0.62) | PDGFRBPDGFRAADKADORA2APIK3CD | |
| SCHEMBL4199482 | 0.73 | RIPK2 (0.39) | KDM4EMEN1ALDH1A1POLBKMT2A | |
| SCHEMBL183087 | 0.71 | PIK3CD (0.58) | PDGFRBPDGFRAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL6182052 | 0.70 | KIT (0.55) | PDGFRBPDGFRAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026346-A1 | THIAZOLIDINE COMPOUNDS, AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-02-26 | — | — | WO | disclosed |
| WO-2009026346-A1 | THIAZOLIDINE COMPOUNDS, AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-02-26 | — | — | WO | disclosed |