Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 2/20 | 0.38 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188009 | 0.81 | PIK3CA (0.41) | RIPK2RIPK3GRM2KDM4ESMN1; SMN2 | |
| SCHEMBL4201155 | 0.80 | PIM1 (0.54) | NPC1HPGDRAB9ACSNK2A2CSNK2B | |
| SCHEMBL4201157 | 0.80 | PIM1 (0.54) | NPC1HPGDRAB9ACSNK2A2CSNK2B | |
| SCHEMBL13951164 | 0.80 | PIM1 (0.54) | NPC1HPGDRAB9ACSNK2A2CSNK2B | |
| SCHEMBL4199482 | 0.79 | RIPK2 (0.39) | RIPK2RIPK3KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL4194980 | 0.76 | ERN1 (0.38) | KDM4ESMN1; SMN2MEN1ALDH1A1POLB | |
| SCHEMBL26315417 | 0.74 | ALDH1A1 (0.48) | KDM4ESMN1; SMN2MEN1ALDH1A1POLB | |
| SCHEMBL2882073 | 0.72 | ADORA2A (0.57) | KDM4ESMN1; SMN2MEN1ALDH1A1POLB | |
| SCHEMBL4201167 | 0.70 | ERN1 (0.40) | RIPK2RIPK3KDM4EMEN1ALDH1A1 | |
| SCHEMBL2877598 | 0.67 | MAP4K4 (0.51) | IP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026346-A1 | THIAZOLIDINE COMPOUNDS, AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-02-26 | — | — | WO | disclosed |
| WO-2009026346-A1 | THIAZOLIDINE COMPOUNDS, AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-02-26 | — | — | WO | disclosed |