Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837071 | 0.94 | TSHR (0.46) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL4191407 | 0.90 | THRB (0.43) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL9469787 | 0.89 | TSHR (0.42) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL4188616 | 0.84 | TSHR (0.36) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL167047 | 0.80 | ALDH1A1 (0.42) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL437536 | 0.80 | POLB (0.45) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL16845611 | 0.79 | TSHR (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL354341 | 0.79 | TSHR (0.41) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL11422102 | 0.79 | TSHR (0.44) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL4193243 | 0.78 | CYP3A4 (0.34) | TSHRALDH1A1CYP3A4HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361246-B1 | ORGANIC POLYMER AND NOVEL POLYMERIZABLE COMPOUND | MITSUI CHEMICALS INC (JP) | 2009-02-18 | — | — | EP | disclosed |
| EP-1361246-B1 | ORGANIC POLYMER AND NOVEL POLYMERIZABLE COMPOUND | MITSUI CHEMICALS INC (JP) | 2009-02-18 | — | — | EP | disclosed |
| US-6797805-B2 | Organic polymers and novel polymerizable compounds | MITSUI CHEMICALS, INC. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1361246-A1 | ORGANIC POLYMER AND NOVEL POLYMERIZABLE COMPOUND | Mitsui Chemicals, Inc. (JP) | 2003-11-12 | — | — | EP | disclosed |
| US-20030166808-A1 | Organic polymers and novel polymerizable compound | MITSUI CHEMICALS, INC. (JP) | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166808-A1 | Organic polymers and novel polymerizable compound | PCNA, UTP18, ODC1 | TSHR 3759/4885ALDH1A1 4350/4885TP53 1113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.