Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196309 | 0.89 | TSHR (0.47) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL9470157 | 0.84 | THRB (0.39) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL11837071 | 0.84 | TSHR (0.46) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL4191407 | 0.84 | THRB (0.43) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL11839585 | 0.80 | BCHE (0.31) | ALDH1A1KDM4E | |
| SCHEMBL17936651 | 0.77 | KMT2A (0.46) | TSHRALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL11828704 | 0.76 | ZDHHC20 (0.36) | TSHRALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL4188616 | 0.75 | TSHR (0.36) | TSHRALDH1A1CYP3A4THRBHPGD | |
| SCHEMBL6754694 | 0.74 | LMNA (0.31) | — | |
| SCHEMBL4200824 | 0.73 | SCN9A (0.34) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244995-A | Vinyl halide aqueous polymerization dispersant system | THE BF GOODRICH COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5155189-A | Derived from repeating units of acrylic and/or methacrylic ester polymers | THE B. F. GOODRICH COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0483051-A1 | Improved vinyl halide aqueous polymerization dispersant system | The Geon Company (US) | 1992-04-29 | — | — | EP | disclosed |
| US-4126595-A | Aqueous coating compositions comprising acrylic oligomers, high molecular weight polymers and crosslinkers | ROHM AND HAAS COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4087397-A | Aqueous coating compositions comprising acrylic oligomers and high molecular weight polymers | ROHM AND HAAS COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-3992333-A | NITROGEN AND SULFUR CONTAINING COPOLYMER IS SELF-CROSSLINKING BINDER | ROHM AND HAAS COMPANY (US) | 1976-11-16 | — | — | US | disclosed |