Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27946217 | 0.85 | CYP2A6 (0.61) | HRH1CHRNB2CHRNA4CYP2A6CHRNA7 | |
| SCHEMBL4205219 | 0.82 | HRH1 (0.51) | HRH1BCHEACHE | |
| SCHEMBL7996307 | 0.82 | CHRNB2 (0.64) | CHRNB2CHRNA4CHRNA7CYP3A4TDP1 | |
| SCHEMBL4369012 | 0.82 | BCHE (0.58) | BCHEACHEMAOB | |
| SCHEMBL10509238 | 0.81 | CHRNB2 (0.72) | CHRNB2CHRNA4CHRNA7CYP3A4TDP1 | |
| SCHEMBL12197592 | 0.81 | CHRNB2 (0.72) | CHRNB2CHRNA4CHRNA7CYP3A4TDP1 | |
| SCHEMBL27928441 | 0.78 | CHRNA7 (0.58) | HRH1CHRNB2CHRNA4CYP2A6CHRNA7 | |
| SCHEMBL4197526 | 0.77 | CHRNB2 (0.42) | CHRNB2CHRNA4KCNA5BCHEACHE | |
| SCHEMBL28230034 | 0.77 | TDP1 (0.67) | HRH1CHRNB2CHRNA4CYP2A6CHRNA7 | |
| SCHEMBL14376115 | 0.77 | CHRNB2 (0.57) | CHRNB2CHRNA4CHRNA7CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093521-A1 | 2, 5-Bis-Diamine [1,4] Benzoquinone-Derivatives | ALMA MATER STUDIORUM - UNIVERISTA'DI BOLOGNA (IL) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093521-A1 | 2, 5-Bis-Diamine [1,4] Benzoquinone-Derivatives | POLQ, DDX5, SDHA | HRH1 3156/4885CHRNB2 4615/4885CHRNA4 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.