Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161217 | 1.00 | TYMS (0.30) | TYMS | |
| SCHEMBL550457 | 1.00 | TYMS (0.30) | TYMS | |
| SCHEMBL1186741 | 1.00 | TYMS (0.30) | TYMS | |
| SCHEMBL2161325 | 1.00 | TYMS (0.30) | TYMS | |
| SCHEMBL550455 | 1.00 | TYMS (0.30) | TYMS | |
| SCHEMBL550456 | 1.00 | TYMS (0.30) | TYMS | |
| SCHEMBL2161144 | 0.85 | CA1 (0.33) | TYMS | |
| SCHEMBL2161147 | 0.85 | CA1 (0.33) | TYMS | |
| SCHEMBL14534477 | 0.85 | CA1 (0.33) | TYMS | |
| SCHEMBL551589 | 0.84 | CA1 (0.32) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| US-7884242-B2 | N1-(6-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylpyridin-3-yl)-3-chloro-N2-[(1S)-1-methyl-2-(methylthio)ethyl]phthalamide; pesticide; nematocide | BAYER CROPSCIENCE AG (DE) | 2011-02-08 | — | — | US | disclosed |
| US-7884242-B2 | N1-(6-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylpyridin-3-yl)-3-chloro-N2-[(1S)-1-methyl-2-(methylthio)ethyl]phthalamide; pesticide; nematocide | BAYER CROPSCIENCE AG (DE) | 2011-02-08 | — | — | US | disclosed |
| US-20090118375-A1 | Optically active phthalamides | BAYER CROPSCIENCE AG (DE) | 2009-05-07 | — | — | US | disclosed |
| US-20090023752-A1 | N-Heterocyclylphthaldiamides as Insecticides | BAYER CROPSCIENCE AG (DE) | 2009-01-22 | — | — | US | disclosed |
| US-20090023752-A1 | N-Heterocyclylphthaldiamides as Insecticides | BAYER CROPSCIENCE AG (DE) | 2009-01-22 | — | — | US | disclosed |
| US-20080051457-A1 | Optically Active Phthalamide Derivative, Agricultural or Horticultural Insecticide, and Method of Using the Same | NAKAO HAYAMI | 2008-02-28 | — | — | US | disclosed |
| US-20080051457-A1 | Optically Active Phthalamide Derivative, Agricultural or Horticultural Insecticide, and Method of Using the Same | NAKAO HAYAMI | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118375-A1 | Optically active phthalamides | CRYZ, CRY1, CRY2 | TYMS 4732/4885 |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | TYMS 4155/4885 |
| US-20090023752-A1 | N-Heterocyclylphthaldiamides as Insecticides | DDT, NQO2, NIT2 | TYMS 2684/4885 |
| US-20080051457-A1 | Optically Active Phthalamide Derivative, Agricultural or Horticultural Insecticide, and Method of Using the Same | CRY1, CNPY2, H1-0 | TYMS 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.