SCHEMBL4196843

SCHEMBL4196843

CC(CC1CCCCC1)NCc1ccccc1NC(=O)Nc1cccc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.52
METAP2 P50579 2/20 0.50
METAP1 P53582 2/20 0.50
KDM4E B2RXH2 8/20 0.46
KMT2A Q03164 5/20 0.46
RORC P51449 2/20 0.45
ALDH1A1 P00352 3/20 0.44
HPGD P15428 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
GSK3B P49841 1/20 0.44
MAPT P10636 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ANPEP P15144 1/20 0.43
MEN1 O00255 2/20 0.43
RAB9A P51151 2/20 0.43
GAA P10253 1/20 0.43
NOX1 Q9Y5S8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4192672 0.90 KMT2A (0.52) EPHX1METAP2METAP1KDM4EKMT2A
SCHEMBL4184474 0.90 TRPV1 (0.48)
SCHEMBL4196799 0.86 CCR3 (0.50) EPHX1KDM4EKMT2ARORCALDH1A1
SCHEMBL4196629 0.86 KMT2A (0.48) METAP2METAP1KMT2AALDH1A1NPSR1
SCHEMBL4197445 0.86 KMT2A (0.48) METAP2METAP1KMT2AALDH1A1NPSR1
SCHEMBL4195095 0.86 KMT2A (0.48) METAP2METAP1KMT2AALDH1A1NPSR1
SCHEMBL4192548 0.83 KMT2A (0.47) METAP2METAP1KDM4EKMT2AALDH1A1
SCHEMBL4193053 0.83 TP53 (0.52) KDM4EKMT2AALDH1A1MAPTMEN1
SCHEMBL4193564 0.82 HTT (0.56) EPHX1KMT2AMAPTMEN1RAB9A
SCHEMBL4195012 0.82 SMN1; SMN2 (0.47) EPHX1KDM4EKMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 EPHX1 1708/4885METAP2 2496/4885METAP1 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.