SCHEMBL4193564

SCHEMBL4193564

CC(CC1CCCCC1)NCc1ccccc1NC(=O)Nc1ccc(F)cc1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.56
CCR3 P51677 9/20 0.50
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
POLB P06746 1/20 0.45
KLK7 P49862 2/20 0.44
EPHX1 P07099 2/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
EPHX2 P34913 1/20 0.42
NPY5R Q15761 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4196799 0.92 CCR3 (0.50) HTTCCR3NPC1RAB9ASMN1; SMN2
SCHEMBL4195012 0.90 SMN1; SMN2 (0.47) HTTCCR3NPC1RAB9ASMN1; SMN2
SCHEMBL4202574 0.89 RAB9A (0.46) HTTCCR3NPC1RAB9ASMN1; SMN2
SCHEMBL4191213 0.88 CCR3 (0.55) CCR3NPC1RAB9ASMN1; SMN2KLK7
SCHEMBL4184490 0.87 MEN1 (0.47) HTTNPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL4193519 0.87 MEN1 (0.47) HTTNPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL4186045 0.85 MEN1 (0.48) HTTSMN1; SMN2KMT2AMEN1
SCHEMBL4185847 0.85 KMT2A (0.47) NPC1RAB9ASMN1; SMN2POLBEPHX1
SCHEMBL4197445 0.85 KMT2A (0.48) HTTCCR3SMN1; SMN2POLBKMT2A
SCHEMBL4196629 0.85 KMT2A (0.48) HTTCCR3SMN1; SMN2POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP claimed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US claimed
EP-1879877-B1 ANTIMICROBIAL AGENTS RANBAXY LAB LTD (IN) 2013-01-02 EP disclosed
US-8076370-B2 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2011-12-13 US disclosed
US-20090215764-A1 Antimicrobial agents RANBAXY LABORATORIES LIMITED (IN) 2009-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215764-A1 Antimicrobial agents TUFM, RPS17, HARS1 HTT 390/4885CCR3 3584/4885NPC1 1859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.