SCHEMBL4196867

SCHEMBL4196867

Cn1c(=O)c(N)c(NCCc2[nH]cc[n+]2C)n1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.37
PTGS2 P35354 1/20 0.37
GAA P10253 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
KDM4E B2RXH2 2/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL943590 0.63 BCHE (0.61) BCHEPTGS2ALDH1A1KDM4ETSHR
SCHEMBL23402694 0.62 BCHE (0.74) BCHEPTGS2GAAALDH1A1KDM4E
SCHEMBL23398749 0.61 BCHE (0.54) BCHEPTGS2GAAALDH1A1KDM4E
SCHEMBL23398382 0.60 BCHE (0.56) BCHEPTGS2GAAALDH1A1KDM4E
SCHEMBL23401048 0.59 BCHE (0.54) BCHEPTGS2GAAALDH1A1KDM4E
Hydrochloric Acid SCHEMBL19744043 0.58 APP (0.33)
SCHEMBL945107 0.57 BCHE (0.71) BCHEPTGS2ALDH1A1KDM4ETSHR
SCHEMBL521938 0.57 CALM1 (0.41) ALDH1A1HPGDKDM4E
Hydrochloric Acid SCHEMBL8151422 0.57 HTR2A (0.37)
Ampyrone SCHEMBL11674586 0.56 BCHE (1.00) BCHEPTGS2GAAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009098257-A1 COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING AT LEAST ONE CATIONIC DIAMINO-N,N-DIHYDROPYRAZOLONE DERIVATIVE L'OREAL (FR) 2009-08-13 WO disclosed